Unlock instant, AI-driven research and patent intelligence for your innovation.

Immunoassay product and process

A technology for immunoassays, devices, applied in the field of immunoassay products and processes, capable of addressing issues such as inhibition of general use and acceptance

Active Publication Date: 2014-01-08
MILLIPORE CORP
View PDF9 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This manifold has a cover with or without a well and a central opening in line with the central opening of the holder, while useful, has limitations that inhibit its general use and acceptance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Immunoassay product and process
  • Immunoassay product and process
  • Immunoassay product and process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0068] first go to figure 1 , shows a carrier 10 according to some embodiments. In the illustrated embodiment, the carrier 10 includes a cover 11 , a carrier top plate 12 , a carrier bottom plate 13 , a cover 14 and a bubble level 15 on the carrier top plate 12 . According to certain embodiments, the carrier 10 is used to keep the blot holder flat and to deliver reagents such as antibodies, wash buffers, etc. to the blot holder. According to certain embodiments, the carrier 10 is a separate component from the manifold base (discussed below), which allows the user to place multiple footprints simultaneously. Thus, each carrier 10 can be selectively loaded with a blot holder containing a blot, its respective antibody added, and then incubated.

[0069] figure 2 The embodiment of the carrier 10 is shown in an open position, the bottom side of the top panel 12 is shown on the left in the figure and the top side of the bottom panel 13 is shown on the right. In the illustrated ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Description

[0001] This application claims priority to Provisional Application Serial No. 61 / 484,701, filed May 11, 2011, the disclosure of which is incorporated herein by reference. technical field [0002] Embodiments disclosed herein relate to devices and processes for detecting and localizing substances contained in blotted membranes. More particularly, it relates to a technique for applying reagents, washes and detection chemistry to blotted membranes to achieve this detection rapidly via the use of vacuum or positive pressure. Background technique [0003] The use of gel electrophoresis is currently a common technique for the separation of biological materials. Non-biological materials can also be separated using gels or other chromatographic supports, but this is a broader effort than biologicals. Typical applications include the isolation of nucleic acid fragments of various sizes in the context of sequence determination; in polymorphic assays; or in size verification in other ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N31/22
CPCG01N33/54366B01L2400/049B01L2300/0809B01L2200/025B01L3/5023B01J20/28035B01J20/28033B01J20/2804G01N33/54391B01L2300/0681B01L2300/126G01N33/56911G01N2469/10G01N2469/20B01L9/52B01L2300/0609B01L2300/069B01L2300/12B01L2400/0487
Inventor C.斯科特P.克拉克K.E.格林尼真R.A.阿马拉R.科隆纳
Owner MILLIPORE CORP