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Chinese patent medicine for treating peptic ulcer and preparation method thereof

A technology of peptic ulcer and Chinese patent medicine, which is applied in the field of medicine and can solve the problems of affecting the efficacy of medicines, large doses of medicines, and inconvenient carrying and taking.

Active Publication Date: 2014-02-12
GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the fact that the original medicinal materials red ginseng and Panax notoginseng are directly ground into the medicine in the original production process, the dosage of the medicine is large, it is inconvenient to carry and take it, the absorption is slow, and the curative effect of the medicine is affected. Modern extraction, separation and preparation technology are urgently needed. , reduce the dosage and improve the curative effect of the drug

Method used

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  • Chinese patent medicine for treating peptic ulcer and preparation method thereof
  • Chinese patent medicine for treating peptic ulcer and preparation method thereof
  • Chinese patent medicine for treating peptic ulcer and preparation method thereof

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Effect test

Embodiment 1

[0022] Embodiment 1 A kind of preparation method of Chinese patent medicine for the treatment of peptic ulcer

[0023] The preparation method of the Chinese patent medicine for the treatment of peptic ulcer of the present invention comprises the following steps:

[0024] (1) Preparation of extract

[0025] Take astragalus, notoginseng and red ginseng according to the proportion of the formula, add 6 times the volume of water, extract twice, each time for 1.5h, filter, and combine the filtrate twice to obtain the extract;

[0026] (2) Separation and concentration

[0027] The extract obtained in step (1) is dialyzed with a 200nm ceramic membrane, and the separation and dialysis parameters are operating pressure 2.0bar, that is, the membrane inlet pressure is 2.5bar, the membrane outlet pressure is 1.5bar, and the feed liquid temperature is 25-50 degrees; Concentrate under reduced pressure at -85°C and 0.09Mpa to an extract with a relative density of 1.20-1.25;

[0028] (3) U...

Embodiment 2

[0038] Embodiment 2 A kind of preparation method of Chinese patent medicine for the treatment of peptic ulcer

[0039] The preparation method of the Chinese patent medicine for the treatment of peptic ulcer of the present invention comprises the following steps:

[0040] (1) Preparation of extract

[0041] Take Astragalus root, Panax notoginseng and red ginseng according to the ratio of the formula, add 10 times the volume of water, extract twice, each time for 2.5 hours, filter, and combine the filtrate twice to obtain the extract;

[0042] (2) Separation and concentration

[0043] Add ethanol to the extract obtained in step (1) so that the ethanol concentration in the solution is 50%, place it for 12 hours after mixing, centrifuge to take the supernatant, evaporate the ethanol in a water bath at 80°C, and concentrate under reduced pressure to a relative density of 1.20-1.25 extract.

[0044] (3) Ultra-finely crushed nacre powder

[0045] Take the nacre powder in the amou...

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Abstract

The invention discloses a Chinese patent medicine for treating peptic ulcer and a preparation method thereof. The Chinese patent medicine mainly comprises radix astragali, pseudo-ginseng, red ginseng, pearl layer powder, and artificial bezoar, and is prepared by steps of extract preparation, separation concentration, ultramicro-crushing of the pearl layer powder, dry paste preparation, and preparation formation. When compared with medicine prepared by original process, the medicine prepared by the method of the invention has decreased dosage and improved medicine curative effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a Chinese patent medicine for treating peptic ulcer and a preparation method thereof. Background technique [0002] Wei Nai An preparation is made of astragalus root, Panax notoginseng, red ginseng, nacre powder and artificial bezoar five-flavor medicinal materials. It is a Chinese patent medicine for treating gastric and duodenal ulcers, chronic gastritis, etc. Chinese Patent No. ZL200510037077.7, the invention patent titled "A Chinese Patent Medicine for Treating Peptic Ulcer and Its Preparation Method" discloses its composition and its preparation method. The disclosed specific preparation method is: decocting astragalus with water Twice, three hours for the first time, two hours for the second time, filter, combine the filtrate, and concentrate into a thick paste; mix the thick paste with red ginseng powder, panax notoginseng powder, and nacre powder, and grind it into 80-120 fine p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P1/04A61K35/413A61K35/56A61K35/618
Inventor 陈蔚文詹若挺苏碧茹林传权严萍王利胜夏荃李茹柳莫全毅邓慧敏赖晓明刘文惠谢洁娜
Owner GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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