New generation of cervical cancer specific early-warning plasma protein

Abstract

The invention discloses a new generation of cervical cancer specific early-warning plasma protein. The protein is selected from any one or any combinations of apoAI, apoE, ATIII, CLU, VIL1 and mTOR. The cervical cancer specific early-warning plasma protein disclosed by the invention as well as a combination thereof can show relatively high specificity, sensitivity and accuracy on early warning of cervical cancer, thus being an excellent indicator for early warning and early diagnosis of cervical cancer tumor.

Description

Technical field [0001] The invention relates to several specific warning plasma proteins for certain diseases and their applications, and belongs to the medical field. Background technique [0002] Cervical cancer is a gynecological malignant tumor, the most common in women in developing countries, and the fatality rate is high. Although the average incidence of cervical cancer in my country is low in the world, the incidence and mortality rate in some areas have been high. Due to the large population of our country, there are about 130,000 new cases each year, accounting for 28% of the world’s total number of cases, which seriously threatens the physical and mental health of women. Since cervical cancer patients are mainly farmers and herders, about 80.0%-90.0% of cases are diagnosed in the middle and late stages. When they are hospitalized, most patients have lost the opportunity for treatment. Early diagnosis is an important prerequisite for effective treatment of cervical c...

AI Technical Summary

Problems solved by technology

[0004] Plasma protein markers are an important content and entry point for oncoproteomics research. Together with tumor tissue-specific markers, they form a tumor marker system. Squamous cell carcinoma-associated antigens (squamous cell carcinoma) for tumor diagnosis Associated antigern (SCC-Ag) plays an important role in the auxiliary diagnosis, recurrence monitoring and prognosis judgment of cervical cancer, and its application is becoming more and more widely. However, the sensitivity and specificity of existing markers in the diagnosis of cervical cancer are not high.

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