Traditional Chinese medicine compound preparation for treating dysmenorrhea and its preparation method and use

A technology for compound preparations and traditional Chinese medicines, which can be used in pharmaceutical formulations, non-central analgesics, medical preparations containing active ingredients, etc., and can solve the problems of backward technology, difficult to determine quality standards, and inaccurate specific efficacy.

Active Publication Date: 2017-11-14
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, although there are some external preparations clinically, they are all clinical reports, the specific curative effect is not exact, the overall technology is relatively backward, and the quality standard is still uncertain, so it is difficult to widely circulate in the market

Method used

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  • Traditional Chinese medicine compound preparation for treating dysmenorrhea and its preparation method and use
  • Traditional Chinese medicine compound preparation for treating dysmenorrhea and its preparation method and use
  • Traditional Chinese medicine compound preparation for treating dysmenorrhea and its preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Weigh 3000g of safflower, 3000g of frankincense, 3000g of myrrh, 3000g of turmeric, 3000g of cassia twig, 4000g of Jiangxiang, 1000g of blood, 3000g of black medicine, 3000g of Yuanhu, 2000g of mugwort leaf, 2000g of asarum, 500g of borneol, and cataplasm Substrate 5500g. Process flow chart such as figure 1 As shown, take the remaining medicinal materials except borneol, add 8 times the amount of water to extract twice, each time for 1 hour, filter the extract, concentrate under reduced pressure to 6kg of extract, and set aside; take borneol and crush through an 80-mesh sieve, set aside; Add borneol to the extract extract, put it into the cataplasm base, stir evenly, apply and slice 1000 pieces, pack to get pain relief patch, and set aside. The finished product is yellow-brown to brown flaky poultice with a fragrant gas.

Embodiment 2

[0018] Weigh 900g of safflower, 900g of frankincense, 900g of myrrh, 900g of turmeric, 900g of cassia twig, 1200g of Jiangxiang, 300g of blood, 900g of black medicine, 900g of peony, 900g of mugwort leaves, 600g of asarum, 600g of borneol, and cataplasm Base 1800g. Process flow chart such as figure 1 As shown, take the remaining medicinal materials except borneol, add 8 times the amount of water to extract twice, each time for 1 hour, filter the extract, concentrate under reduced pressure to 2.5kg of extract, and set aside; take borneol and crush it through an 80-mesh sieve, set aside Add borneol to the extract extract, put it into the cataplasm matrix, stir evenly, apply and slice 350 pieces, pack to get pain relief patch, and set aside. The finished product is yellow-brown to brown flaky poultice with a fragrant gas.

Embodiment 3

[0020] Weigh 800g of safflower, 800g of frankincense, 800g of myrrh, 800g of turmeric, 800g of cassia twig, 800g of incense, 500g of blood, 800g of black medicine, 950g of rhubarb, 500g of mugwort leaves, 500g of asarum, 475g of borneol, and cataplasm Base 1500g. Take the remaining medicinal materials except borneol, add 8 times the amount of water to extract twice, each time for 1 hour, filter the extract, concentrate under reduced pressure to 2kg of extract, and set aside; take the borneol and crush it through an 80-mesh sieve, set aside; extract Add borneol to the extract, put it into the cataplasm base, stir evenly, apply and slice 300 pieces, pack to get pain relief patch, and set aside. The finished product is yellow-brown to brown flaky poultice with a fragrant gas.

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Abstract

The invention discloses a traditional Chinese medicine compound formulation for treating dysmenorrhea. The traditional Chinese medicine compound formulation is prepared from the following crude drugs in parts by weight: 1-15 parts of flos carthami, 1-15 parts of olibanum, 1-15 parts of myrrh, 1-15 parts of rhizoma wenyujin concisum, 1-15 parts of cassia twig, 1-15 parts of lignum dalbergiae odoriferae, 1-9 parts of resina draconis, 1-15 parts of lindera aggregate, 1-18 parts of rhizoma corydalis, 1-9 parts of folium artemisiae argyi, 1-9 parts of as arum and 0.5-9 parts of borneol. By adopting the traditional Chinese medicine formulation, the twister reaction times of dysmenorrhea model rats can be obviously reduced, uterine contractions rhythm disorders can be coordinated by adjusting the balance of prostaglandin level inside a sufferer body by inference, meanwhile, the neuropeptide P substance level is reduced by interaction between the systems in an immune neural network, and proinflammatory cytokines such as 1L-1beta are reduced, so as to achieve the target of treating dysmenorrhea. The invention also discloses a preparation method and use of the traditional Chinese medicine compound formulation.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating dysmenorrhea; in addition, the invention also relates to a preparation method and a medical application of the traditional Chinese medicine compound preparation. Background technique [0002] Primary Dysmenorrhea refers to cramping pain in the lower abdomen and waist before and during menstruation, accompanied by nausea, vomiting, and cold extremities in severe cases, and without obvious pelvic organic diseases (such as endometriosis) Wait). It is more common in unmarried or childless young women. The incidence rate of primary dysmenorrhea is 43% to 90% in foreign reports, and 33.19% in domestic reports, of which primary dysmenorrhea accounts for 36.06%. In addition, 80% of patients with endometriosis are accompanied by dysmenorrhea and chronic pelvic pain. Among them, progressively aggravated dysmenorrhea seriously affects the quality of life of female patients....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/70A61P15/00A61P29/00
Inventor 蔡小荪付金荣
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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