Femtosecond laser mode adjustable optical tweezers control device based on column vector light beam

Abstract

The invention discloses a femtosecond laser mode adjustable optical tweezers control device based on a column vector light beam and relates to an optical tweezers technology for optical control particles and cells. The device solves the problem that the power of an incident laser needs to be increased to increase the trapping force of a pair of optical tweezers according to a traditional tweezers technology, but irretrievable thermal damage will be caused to a controlled object though the trapping force is increased. A seed light source provided with a femtosecond laser device is adjusted through a diaphragm, an attenuation piece and a first 800 nm holophote and is then split into a reflected laser and a transmitted laser through a first beam splitter, the transmitted laser is converted into the column vector light beam through a polarization converter, the column vector light beam enters a microscope after being adjusted by a second beam splitter, a shutter and a fourth 800 nm holophote, and the reflected laser enters the microscope after being adjusted by a second 800 nm holophote, a third 800 nm holophote, the second beam splitter, the shutter and the fourth 800 nm holophote. The device is suitable for research in the life science field.

Description

technical field [0001] The invention relates to optical tweezers technology for optically manipulating particles and cells. Background technique [0002] Since the emergence of optical tweezers technology, optical tweezers have been widely used in life sciences, medicine, physics, materials and nanoscience due to their non-contact and non-destructive manipulation of micro-nano-scale particles, and are considered to be the most ideal single molecule , single cell, particle, micro-nano device manipulation technology. [0003] Optical tweezers mostly use continuous laser and long pulse laser. Compared with continuous laser and long pulse laser, femtosecond laser pulse has extremely short pulse width, high peak power and time and space resolution, and can accurately detect Control action energy. At present, using a high repetition rate femtosecond laser as a light source can achieve stable capture of red blood cells, white blood cells, viruses, polystyrene microspheres, etc. ...

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem that the traditional optical tweezers technology improves the capturing force of the optical tweezers by increasing the incident laser power, while the capturing force is increased, it will cause irreparable thermal damage to the manipulated object, and proposes a method based on cylindrical vector beam Femtosecond laser mode tunable optical tweezers manipulation device

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