Povidone iodine and preparation method and application thereof
A technology of povidone iodine and polyvinylpyrrolidone, which is applied in the field of preparation of povidone iodine, can solve the problems of substandard stability, etc., and achieve the effects of poor stability, convenient use and good stability
Inactive Publication Date: 2014-11-19
WUHAN NEWLAND EPM
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Problems solved by technology
However, povidone-iodine powder has a problem of substandard stability when producing low-concentration solutions such as povidone-iodine disinfectant
Method used
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Experimental program
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Embodiment 1
[0014] The formula of povidone-iodine: polyvinylpyrrolidone k30: 10%, iodine: 2.34%, potassium iodide 1.17%, solvent n-propanol: 5.0%, stability aid: 0.01%, and the balance is water.
Embodiment 2
[0016] The formula of povidone-iodine: the mass percent of each component consists of: polyvinylpyrrolidone k30: 50.0%, iodine: 11.44%, potassium iodide 5.72%, solvent n-propanol: 45.0%, stability aid: 10.0%, surplus The amount is water.
Embodiment 3
[0018] The formula of povidone-iodine: the mass percent of each component is composed of: polyvinylpyrrolidone k30: 30.0%, iodine: 8%, potassium iodide 4%, solvent n-propanol: 35.0%, stability aid: 5.0%, surplus The amount is water.
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The invention discloses a povidone iodine, which comprises the following components: 10.0%-50.0% of polyvinylpyrrolidone k30, 2.34%-11.44% of iodine, 1.17-5.72% of potassium iodide, 5.0-45.0% of a solvent n-propanol, 0.01%-10.0% of a stability auxiliary agent and the balance of water. The invention also discloses a preparation method of povidone iodine. The preparation method of povidone iodine provided by the invention employs a solution method for complex of polyvinylpyrrolidone, iodine and additives under certain conditions, so as to prepare a povidone iodine solution; povidone iodine obtained by complexation of povidone and iodine has good stability, meets the requirements of the medical disinfection industry on povidone iodine, and solves the problem of poor stability of povidone iodine. At the same time, povidone iodine prepared by water solution method is more convenient for usage.
Description
technical field [0001] The invention relates to a preparation method of povidone-iodine and its preparation method and application. Background technique [0002] The current method of domestic production of povidone-iodine is a solid method, that is, polyvinylpyrrolidone, iodine and auxiliary agents are used to produce povidone-iodine powder by milling. But povidone-iodine powder has the problem that the stability is not up to standard when producing low-concentration solutions such as povidone-iodine disinfectant. Contents of the invention [0003] One of purposes of the present invention is to provide a kind of preparation method of povidone-iodine and its preparation method, application. [0004] According to one aspect of the present invention, a kind of povidone iodine is provided, and the mass percent of each component is composed of: polyvinylpyrrolidone k30: 10.0%~50.0%, iodine: 2.34%~11.44%, potassium iodide 1.17~5.72%, solvent n-propanol: 5.0-45.0, stability ai...
Claims
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IPC IPC(8): A61K31/79A61K9/08A61K9/20A61K8/81A01N59/12A61P31/02A61P1/02A01P1/00A61Q11/00A01P3/00
Inventor 陈丽君
Owner WUHAN NEWLAND EPM
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