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Traditional Chinese medicine for treating damp-heat type 2 diabetes mellitus and preparation method thereof

A type 2 diabetes and damp-heat intrinsic technology, applied in the field of pharmacy, can solve problems such as hypoglycemia, human damage, fatigue and weakness, and achieve simple, easy-to-accept, and highly targeted effects

Inactive Publication Date: 2014-12-10
济南高天机械设备有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 2. envirnmental factor
[0011] 2. fatigue, obesity
[0019] There are many medicines for treating diabetes in Western medicine, such as sulfonylureas, biguanides, Xiaoke pills, etc. Although these medicines can significantly improve the symptoms of diabetes patients such as "three excesses and one deficiency" and control the decline of blood sugar indicators, most of these medicines are chemical medicines. Or contain chemicals, sometimes hypoglycemia reaction occurs, and excreted by the kidneys, long-term use will cause certain damage to the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0071] Wherein, when the dosage form of the traditional Chinese medicine is a honey-refined pill, its preparation method comprises the following steps:

[0072] Step 1: First mix Wangjiangnan, Coptis chinensis, American ginseng, Huoxiang, Atractylodes macrocephala, Coix seed, Panax notoginseng, Fotan motherwort and Gentiana according to the stated ratio, and then distill and crystallize to obtain powder;

[0073] Step 2: Take the remaining raw materials and mix them according to the ratio, add 2-6 times the amount of 83-94% ethanol to soak for 1-2 hours, heat and extract twice, each time for 1-1.5 hours, and combine the extracts , 124-150 mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 4400-98000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.04 at 87°C, which becomes component 1;

[0074] Step 3: Soak the dregs of the traditional Chinese medicine in step 2 ...

Embodiment 1

[0086] Embodiment 1 honey refining pill of the present invention

[0087] Take Wangjiang 15g, Coptidis 27g, American ginseng 37g, Huoxiang 27g, Atractylodes macrocephala 34g, Coix seed 20g, Panax notoginseng 25g, Motherwort 7g, Gentiana 23g, Angelica 36g, Astragalus 31g, Akebia 16g, Plantago 30g , Alisma 27g, Ponytail 9g, Berberis 4g, Nandina root 7g, Sanbaicao 10g, Dawan flower stem 9g.

[0088] Its preparation method comprises the following steps:

[0089] Step 1: First mix Wangjiangnan, Coptis chinensis, American ginseng, Huoxiang, Atractylodes macrocephala, Coix seed, Panax notoginseng, Fotan motherwort and Gentiana according to the stated ratio, and then distill and crystallize to obtain powder;

[0090] Step 2: Take the remaining raw materials and mix them according to the stated ratio, add 94% ethanol twice the amount of the mixture, soak for 1-22 hours, heat and extract twice, each time for 1 hour, combine the extracts, filter through 150 mesh, After ultrafiltration ...

Embodiment 2

[0093] Embodiment 2 Granules of the present invention

[0094] Take Wangjiangnan 25g, Coptidis 35g, American ginseng 29g, Huoxiang 30g, Atractylodes macrocephala 29g, Coix seed 23g, Panax notoginseng 18g, Motherwort 10g, Gentiana 18g, Angelica 39g, Astragalus 27g, Akebia 23g, Plantago 32g , Alisma 34g, Maweilian 12g, Berberis 13g, Nandina root 4g, Sanbaicao 4g, Dawan flower stem 7g.

[0095] Its preparation method comprises the following steps:

[0096] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 4 times that of the mixture and 85% ethanol, heat to boiling and reflux for 4 hours, filter, and use percolation method at a rate of 2ml per minute. Percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.09Mpa to a paste with a relative density of 1.10 at 60°C, spray dry, the air inlet temperature of the spray dryer is 160°C, and the air outlet temperature is 85°C, then Crushed...

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Abstract

The invention discloses a traditional Chinese medicine for treating the damp-heat type 2 diabetes mellitus and a preparation method thereof. The traditional Chinese medicine comprises the following raw herbal materials: coffee senna, the rhizome of Chinese goldthread, American ginseng, agastache rugosa,, bighead atractylodes rhizome, coix seed, pseudo-ginseng, Chinese knotweed herb, gentian, Chinese angelica, astragalus mongholicus, aristolochiae lignum, plantain seeds, rhizoma alismatis, manyleaf meadowure rhizome and root, berberis thunbergii, common nandina root, Chinese lizardtail rhizome and calystegia hederacea stem. The traditional Chinese medicine has the benefits that the traditional Chinese medicine has effects of invigorating spleen and supplementing qi and eliminating dampness and heat, mainly treats the damp-heat type 2 diabetes mellitus and regulates the blood sugar; the traditional Chinese medicine removes the root causes, has strong pertinence, directly takes medicine effects on the focus and has an obvious curative effect; the traditional Chinese medicine adopts Chinese herbal medicines, and is rich in medicine source, safe and effective, low in price, difficult to generate drug resistance, simple to prepare, convenient for administration and easy to accept by a patient.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating damp-heat intrinsic type 2 diabetes and a preparation method thereof. Background technique [0002] Diabetes mellitus (diabetes mellitus) has become a common and frequently-occurring disease with a mortality rate second only to cancer, AIDS and cardiovascular diseases in many countries in the world. Since the early 1980s, the prevalence of diabetes in my country has increased by 5 times. There are nearly 100 million diabetics, making it the second largest country in the world with diabetes. Diabetes is equivalent to Diabetes Syndrome in traditional Chinese medicine. Pathologically, it is based on yin deficiency and characterized by dryness and heat. If it damages the five internal organs, various complications will occur, such as cataract, bird blindness, carbuncle, hypertension, myocardial infarction, etc. Diabetes has long been recor...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P3/10
Inventor 柏焕焕
Owner 济南高天机械设备有限公司
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