System and method for precise dose distribution modulation in radiotherapy

A radiation therapy and dose distribution technology, applied in X-ray/γ-ray/particle irradiation therapy, etc., can solve the problem of inaccurate dose delivery in tumor target areas, achieve the effect of reducing treatment time, accurate dose distribution, and realizing dose distribution
CN104258508BActive Publication Date: 2017-03-15HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
Publication Date
2017-03-15

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Abstract

The invention relates to a modulating method and system for accurate dose distribution in the radiation therapy. According to the method, in the fractionated therapy positioning process, a 4D CBCT image of a patient is obtained, and a target region movement model is constructed in combination with a breathing movement signal; in the fractionated therapy process, the breathing movement signal and a non-autonomy movement signal of the patient are monitored in real time through an optical positioning system, with the help of the target region movement model, the movement position of a tumor is rapidly predicted, the positions of blades of a multi-blade collimator are adjusted in real time, and therefore ray bundles closely track the tumor for accurate therapy. In the whole therapy process, the patient freely breaths, an accelerator emits the bundles constantly, in this way, the therapy time is shortened, dose errors which are caused by the breathing movement and non-autonomy movement of the patient in the therapy are eliminated, and accuracy of the radiation therapy is improved.
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Description

technical field

[0001] The invention relates to the technical field of radiotherapy equipment improvement, in particular to a precise dose distribution modulation system and method in radiotherapy. Background technique

[0002] The patient's respiratory movement and involuntary movement during radiotherapy can cause changes in the tumor location, resulting in insufficient doses received by the tumor target area or over-irradiation of normal tissues and organs, which increases the recurrence rate of tumors and the incidence of radiotherapy complications. In order to reduce the uncertainty of dose delivery in the target area due to respiratory movement and involuntary movement, the first commonly used method in clinical practice is the target area expansion method, which draws a sufficiently large target area boundary to fully cover the patient's respiratory movement. and the range of tumor displacement caused by involuntary movement, but this will cause the patient's normal t...

Claims

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