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System and method for precise dose distribution modulation in radiotherapy

A radiation therapy and dose distribution technology, applied in X-ray/γ-ray/particle irradiation therapy, etc., can solve the problem of inaccurate dose delivery in tumor target areas, achieve the effect of reducing treatment time, accurate dose distribution, and realizing dose distribution

Active Publication Date: 2017-03-15
HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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Problems solved by technology

[0003] The purpose of the present invention is to solve the problem of inaccurate dose delivery in the tumor target area caused by the patient's respiratory movement and involuntary movement in a fast and non-invasive way in the existing radiotherapy technology, and provides a radiotherapy Precise dose distribution modulation system and method

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  • System and method for precise dose distribution modulation in radiotherapy
  • System and method for precise dose distribution modulation in radiotherapy

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Embodiment Construction

[0029] The present invention will be further described below in conjunction with accompanying drawing and specific embodiment:

[0030] Such as figure 1As shown, the precise dose distribution modulation system in radiotherapy of the present invention includes a medical accelerator target source 1, a multi-leaf collimator 2, a pulsed KV class X-ray machine 3, an X-ray flat panel detector 4, an optical positioning system 5, Treatment couch 6, high-performance PC server 7; wherein medical accelerator target source 1 is an X-ray photon source generated by high-energy electron targeting through the bremsstrahlung effect; multi-leaf collimator 2 is used as a beam collimation device, which can adjust multiple The position of the blade sequence of the leaf grating and the movement mode of the whole machine displacement form a predetermined beam direction and beam shape treatment beam; the pulse type KV-level X-ray machine 3 and X-ray flat panel detector 4 serve as the patient's two-di...

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Abstract

The invention relates to a modulating method and system for accurate dose distribution in the radiation therapy. According to the method, in the fractionated therapy positioning process, a 4D CBCT image of a patient is obtained, and a target region movement model is constructed in combination with a breathing movement signal; in the fractionated therapy process, the breathing movement signal and a non-autonomy movement signal of the patient are monitored in real time through an optical positioning system, with the help of the target region movement model, the movement position of a tumor is rapidly predicted, the positions of blades of a multi-blade collimator are adjusted in real time, and therefore ray bundles closely track the tumor for accurate therapy. In the whole therapy process, the patient freely breaths, an accelerator emits the bundles constantly, in this way, the therapy time is shortened, dose errors which are caused by the breathing movement and non-autonomy movement of the patient in the therapy are eliminated, and accuracy of the radiation therapy is improved.

Description

technical field [0001] The invention relates to the technical field of radiotherapy equipment improvement, in particular to a precise dose distribution modulation system and method in radiotherapy. Background technique [0002] The patient's respiratory movement and involuntary movement during radiotherapy can cause changes in the tumor location, resulting in insufficient doses received by the tumor target area or over-irradiation of normal tissues and organs, which increases the recurrence rate of tumors and the incidence of radiotherapy complications. In order to reduce the uncertainty of dose delivery in the target area due to respiratory movement and involuntary movement, the first commonly used method in clinical practice is the target area expansion method, which draws a sufficiently large target area boundary to fully cover the patient's respiratory movement. and the range of tumor displacement caused by involuntary movement, but this will cause the patient's normal t...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N5/10
Inventor 任强贾婧王玉裴曦吴宜灿
Owner HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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