Preparation process of Xuhanting capsule (medicine for treating abnormal sweating)

Abstract

The invention discloses a preparation process of a Xuhanting capsule (medicine for treating abnormal sweating). The preparation process comprises the following steps: (S1) mixing four raw materials including radix astragali, blighted wheat, Chinese date and glutinous rice roots, adding water into the mixture and extracting for three times; adding water to calcined oyster shells and extracting for three times; and filtering liquid medicine after each extraction process and collecting filtrates; (S2) carrying out alcohol precipitation, so as to obtain an extract, wherein the relative density of the extract is 1.05-1.10; (S3) carrying out spray drying on two thirds of the extract to prepare extract powder; (S4) adding an additive into the extract powder, stirring in a stirring machine, preparing the rest extract into a wetting agent, and granulating uniformly mixed dextrin and extract; and (S5) filling the capsule. According to the preparation process, inactive ingredients are removed by virtue of the alcohol precipitation on the water-extracted liquid medicine, so that the orally-taken dosage of a finished capsule product is reduced, the content of active ingredients in the extract powder is increased, the injury of impurities in the medicine to the human health is reduced, energy is saved, the energy consumption is reduced, and the labor productivity is increased; the method is simple and is short in cycle; conventional pharmaceutical operation and instruments are used, the industrial mass production is easily realized.

Description

technical field [0001] The invention belongs to the technical field of Chinese patent medicines, and relates to a preparation method of Chinese patent medicines, in particular to a manufacturing process of Xuhanting Capsules. Background technique [0002] Under normal circumstances, the sweat glands secrete a certain amount of sweat to maintain the humidity of the human skin and excrete certain metabolites; "Su Wen·Yin and Yang Different Theory" says: "Yang added to yin is called sweat", indicating that sweat is the result of yang qi steaming body fluid from Formed by the discharge of sweat pores. Excessive sweating, however, is abnormal in certain disease processes. Spontaneous sweating is caused by excess of yin and yang, deficiency of yin and yang, loss of balance between camp and defense, and leakage of body fluid. Just like Jingyue Quanshu said: "All ancient methods say: people who sweat spontaneously are Yang deficiency, and interstitial muscles are not solidified by...

AI Technical Summary

Problems solved by technology

[0004] 1. The calcined oysters are not calcined until they are crispy, which makes it difficult to fully extract the active ingredients by water extraction of the calcined oysters;

[0005] 2. The extraction parameters of traditional Chinese medicine are not clear and standardized, which leads to low yield of ointment and low content of active ingredients;

[0006] 3. The water-extracted medicinal liquid has not been alcohol-precipitated to remove ineffective ingredients, resulting in a large oral dose of the finished capsule and less active ingredients in the extract powder;

[0007] 4. The advanced Chinese medicine extract spray drying technology is not adopted in the extraction of powder, and the old technology is used to dry in a high-temperature oven, resulting in high-temperature damage and loss of active ingredients;

[0008] 5. The old granulation process adopts high-temperature drying, and the content of active ingredients often cannot meet the minimum requirements of the standard;

[0009] 6. Incorrect selection of capsule filling parameter ratio, resulting in the difference limit of filling volume exceeding the standard;

[0010] 7. Long production time, large material loss, high energy consumption and high production cost

Images