Blood fat-lowering and liver-protecting composite as well as preparation prepared thereby and preparation method of preparation

A composition and preparation technology, applied in the field of traditional Chinese medicine, can solve problems such as obvious side effects, complex ingredients, and complicated preparation process, and achieve the effects of clear active ingredients, small oral doses, and convenient portability

Inactive Publication Date: 2013-04-24
SHENZHEN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] At present, there are many drugs that can lower blood lipid or treat chemical liver injury alone, but there are few drugs that can simultaneously lower blood lipid and treat chemical liver injury. The existing products more or less have the following problems: High, unstable effect, obvious side effects, etc.
Among them, traditional Chinese medicines that can lower blood fat and protect the liver at the same time are often large prescriptions, with complex ingredients, resulting in a very complicated preparation process, such as Ganshu Capsules, the main medicinal materials are hawthorn, dandelion, gardenia, jujube seed, turmeric, orange peel, bergamot, Panax notoginseng, magnolia officinalis, rhubarb; and the traditional Chinese medicine composition described in CN200510134267, which is made of raw materials such as red yeast rice, gynostemma, kudzu root, chrysanthemum, dandelion and Alisma
At the same time, these traditional Chinese medicines often contain nourishing ingredients, and these ingredients need to be absorbed by the liver to take effect. Too much of these ingredients will often increase the burden on the liver, which is not conducive to the recovery of liver function.

Method used

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  • Blood fat-lowering and liver-protecting composite as well as preparation prepared thereby and preparation method of preparation
  • Blood fat-lowering and liver-protecting composite as well as preparation prepared thereby and preparation method of preparation
  • Blood fat-lowering and liver-protecting composite as well as preparation prepared thereby and preparation method of preparation

Examples

Experimental program
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preparation example Construction

[0088] 3. Preparation of lipid-lowering and liver-protecting composition preparation.

[0089] 1. Preparation of Example 9 in Table 2.

[0090] Put 10 parts of Panax notoginseng saponins, 6 parts of tea polyphenols, 5.2 parts of microcrystalline cellulose, 7 parts of medicinal starch, and 1.5 parts of carboxymethyl starch sodium into a three-dimensional motion mixer and mix for 15-45 minutes to obtain a mixed powder; Put the mixed powder in the granulator, and while stirring, add an appropriate amount of 75% ethanol solution to obtain wet granules; put the wet granules in a hot air circulation drying oven at 65°C to dry until the water content is less than 3.5%, and then granulate, granulate After completion, add 0.3 part of magnesium stearate, mix well, and fill the capsules to obtain capsules.

[0091] 2. Preparation of Example 10 in Table 2.

[0092] Put 10 parts of Panax notoginseng saponins, 6 parts of tea polyphenols, 10 parts of microcrystalline cellulose, 8 parts...

Embodiment 9

[0130] Embodiment 9 is a hard capsule, and compared with the above-mentioned 15 kinds of hard capsule health products, it has the following advantages:

[0131] a. The prescription is simple. The prescription for this product only includes Panax notoginseng and green tea. The above-mentioned products, except the broken ganoderma lucidum spore capsules and chitosan oligosaccharide ginkgo biloba capsules, are all based on large prescriptions, ranging from 5 to 10;

[0132] b. The main ingredients are clear. This product is obtained from the natural plants of Panax notoginseng and green tea, respectively, to obtain the total saponins of Panax notoginseng and tea polyphenols. The hypolipidemic effect of tea polyphenols and the protective effect of Panax notoginseng saponins on chemical liver injury are clear;

[0133] c. Small dosage, easy to carry and take. This product, 2 times a day, 1 capsule each time. The above-mentioned products, except the broken ganoderma lucidum spo...

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Abstract

The invention provides a blood fat-lowering and liver-protecting composite as well as a preparation prepared thereby and a preparation method of the preparation, belonging to the technical field of traditional Chinese medicines. At present, in Chinese material medical preparations with the effects of lowering blood fat and protecting liver, most of the Chinese material medical preparations are costly prescription and has complicated components and backward process, contains nutritious components, and increases the load of the liver due to excessive components. The blood fat-lowering and liver-protecting composite provided by the invention comprises the following raw materials in parts by weight: 90-130 parts of pseudo-ginseng and 30-70 parts of tea. The preparation prepared from the composite comprises active ingredients and pharmaceutic adjuvants, wherein the active ingredients comprise the following components in parts by weight: 4-13 parts panax notoginseng saponins (PNS) and 2-8 parts of tea polyphenol (TP). The blood fat-lowering and liver-protecting composite and the preparation provided by the invention have the advantages of clear active ingredients, good stability, controllable quality and less dosage, and are convenient to use and carry.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a lipid-lowering and liver-protecting composition, a preparation and a preparation method thereof. Background technique [0002] At present, with the continuous improvement of people's living standards, patients with hyperlipidemia are becoming more and more common, including hypercholesterolemia, hypertriglyceridemia and compound hyperlipidemia, which is the cause of atherosclerosis One of the main factors of sclerosis and coronary heart disease. [0003] Excessive blood lipids can easily cause "thick blood", deposit on the blood vessel wall, and gradually form small plaques (that is, what we often call "atherosclerosis"). These "plaques" increase and increase, gradually blocking blood vessels, causing Blood flow slows down, and in severe cases, blood flow is interrupted. If this happens in the heart, it will cause coronary heart disease; if it happens in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61P1/16A61P3/06
Inventor 任茜
Owner SHENZHEN INST OF TECH
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