Adaptive target area conversion method combining image segmentation and deformation registration technology

A deformation registration, target area technology, applied in image analysis, image enhancement, image data processing and other directions, can solve the problems of adjusting the positioning error, not achieving self-adaptation, time-consuming and labor-intensive, and achieving the effect of accurate liver boundary

Active Publication Date: 2015-03-11
SHANDONG NORMAL UNIV
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Problems solved by technology

Clinically, the image-guided radiotherapy technology based on CBCT (Cone beam CT) is mainly used, but at present, this technology is only used to adjust the setup error, that is, to perform rigid body registration based on the bone shape between the planned CT and the KV-level CBCT obtained before radiotherapy. Then the positioning is guide

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  • Adaptive target area conversion method combining image segmentation and deformation registration technology
  • Adaptive target area conversion method combining image segmentation and deformation registration technology
  • Adaptive target area conversion method combining image segmentation and deformation registration technology

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[0054] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0055] For thoracic and abdominal tumors, the main organ at risk during radiotherapy is the liver. A normal liver atlas was established through 50 sets of CT images, and the atlas-based segmentation algorithm was used to achieve automatic segmentation of the liver tissue region in the planned CT of the patient. The method combined with the likelihood function model automatically extracts the thoracic and abdominal tumor regions on the planned CT to achieve the purpose of automatic segmentation of the planned CT. Afterwards, the deformation registration method based on the orthogonal wavelet basis function is used to automatically transfer various information in the planned CT to the CBCT through the calculated deformation domain.

[0056] The specific steps are as figure 1 shown:

[0057] Step 1: In order to realize the automatic segmentation of liver t...

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Abstract

The invention discloses an adaptive target area conversion method combining image segmentation and a deformation registration technology. According to the method, a threatening organ and a thoracic and abdominal tumor area are segmented automatically; multi-modal registration is performed on CBCT (Cone Beam Computed Tomography) images and planed CT (Computed Tomography) images by adopting a deformation registration algorithm; information on the planned CT is automatically transferred to the CBCT according to the calculated deformation area. After the rigid registration of the planed CT and the CBCT images, in order to compensate the deformation range which cannot recover, the transfer of a threatening organ, a tumor profile and a radiation treatment plan from the planned CT to CBCT is realized by adopting an orthogonal wavelet basis function-based deformation registration algorithm through the calculated deformation domain, so that a target position is accurately positioned.

Description

technical field [0001] The invention relates to an adaptive target area conversion method combining image segmentation and deformation registration technology. Background technique [0002] The goal of clinical precision radiotherapy is to maximize the radiation absorption dose of the tumor target area while reducing the radiation absorption dose to the organs at risk as much as possible. For thoracic and abdominal tumors, the current clinical practice is to first locate CT, and then perform successive irradiation according to the formulated radiotherapy plan. However, in the course of radiotherapy, due to the movement and deformation of organs or various objective factors, the tumor and the organ at risk (mainly the liver) deviate from the field of radiation, resulting in under-dose irradiation of the tumor and over-dose of the organ at risk. [0003] Using the image-guided radiation therapy (IGRT) technology developed in recent years, the tumor target area and organs at r...

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Application Information

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IPC IPC(8): G06T7/00
CPCG06T7/30G06T7/77G06T2207/10081G06T2207/30056G06T2207/30096
Inventor 李登旺石雪陈进琥李洪升尹勇
Owner SHANDONG NORMAL UNIV
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