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A pharmaceutical composition for treating sequelae of cardiac bypass and preparation method thereof

A technology of heart bypass and composition, which is applied in the field of pharmaceutical composition and its preparation, and can solve problems such as no treatment, no cure, and no curative effect

Active Publication Date: 2017-11-07
BOZHOU YONGGANG PIECES FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine has no suitable treatment method and cannot cure
The medicine of the motherland is extensive and profound. Through the combination of prescriptions, the research on the treatment of myocardial ischemia after heart bypass surgery has just begun, and there is no drug with confirmed efficacy.

Method used

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  • A pharmaceutical composition for treating sequelae of cardiac bypass and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 1. Prescription:

[0025] 180g safflower, 120g astragalus, 100g angelica, 100g rehmannia, 80g yizhiren, 60g shayuanzi, 50g dodder, 90g yam, 60g poria cocos, 70g hawthorn, 70g sealwort, 60g mulberry, 30g earthworm, 30g earthworm, 40g leech , licorice 100g.

[0026] 2. Preparation method:

[0027] Safflower, yam, Poria cocos, wood beetle, earthworm, and leech are crushed into fine powder and sieved. The remaining ten flavors were decocted twice, 30 minutes each time, concentrated, precipitated with 50% alcohol, filtered, and the filtrate was concentrated and spray-dried. Mix well, make granules, dry, and make 1000 pieces, that is to say.

Embodiment 2

[0029] 1. Prescription:

[0030] 120g safflower, 100g astragalus, 90g angelica, 90g rehmannia, 70g yizhiren, 80g sand garden seed, 50g dodder seed, 80g yam, 100g poria cocos, 90g hawthorn, 60g sealwort, 50g mulberry, 40g earthworm, 40g earthworm, 40g leech , licorice 90g.

[0031] 2. Preparation method:

[0032] After decocting the above fifteen flavors, concentrate, precipitate with 50% alcohol, filter, concentrate the filtrate, decoct safflower separately, mix the two, filter, and make 1000ml of oral liquid.

Embodiment 3

[0034] 1. Prescription:

[0035] 110g of safflower, 80g of astragalus, 80g of angelica, 70g of Rehmannia glutinosa, 70g of Yizhiren, 70g of sand garden seed, 60g of dodder seed, 100g of yam, 80g of poria cocos, 60g of hawthorn, 90g of sealwort, 60g of mulberry, 40g of earthworm, 50g of earthworm, 60g of leech , licorice 60g.

[0036] 2. Process:

[0037] Safflower, yam, Poria cocos, wood beetle, earthworm, and leech are crushed into fine powder and sieved. The remaining ten flavors are decocted in water, concentrated, precipitated with 50% alcohol, filtered, concentrated the filtrate, mixed with the combined medicine powder, made into water pills, and made into 1000 capsules, to get ready.

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PUM

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Abstract

The invention aims at disclosing a pharmaceutical composition for treating the sequelae of heart pass and a preparation method thereof. The pharmaceutical composition disclosed by the invention is prepared from the following active pharmaceutical ingredients in parts by weight: 120-220 parts of safflower, 80-180 parts of radix astragali, 80-120 parts of radix angelicae sinensis, 80-150 parts of radix rehmanniae preparata, 50-100 parts of fructus alpiniae oxyphyllae, 50-100 parts of flatstem milkvetch seed, 30-100 parts of semen cuscutae, 30-160 parts of rhizoma dioscoreae, 30-120 parts of poria cocos, 30-120 parts of fructus crataegi, 30-100 parts of rhizoma polygonati, 20-120 parts of mulberry, 30-90 parts of ground beeltle, 10-80 parts of earthworm, 10-80 parts of leech and 30-150 parts of radix glycyrrhizae. The medicine disclosed by the invention can be added with conventional accessories and prepared into clinically acceptable tablets, granules, pills, capsules, oral liquid and the like according to a conventional process.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating sequelae of cardiac bypass and a preparation method thereof. Background technique [0002] Bypass surgery, as the name suggests, is to take the patient's own blood vessels (such as the internal thoracic artery, the great saphenous vein of the lower limbs, etc.) or blood vessel substitutes, and connect the distal end of the narrowed coronary artery to the aorta, allowing blood to pass through the narrowed part. Reach the ischemic site, improve myocardial blood supply, and then achieve the purpose of relieving angina symptoms, improving heart function, improving the quality of life of patients and prolonging life. This operation is called coronary artery bypass grafting, which establishes a smooth path between the aortic root full of arterial blood and the ischemic myocardium. Therefore, some people vividly ca...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61P9/10A61K35/62A61K35/64
CPCA61K9/08A61K9/2095A61K35/62A61K36/076A61K36/232A61K36/286A61K36/39A61K36/481A61K36/484A61K36/605A61K36/734A61K36/804A61K36/8945A61K36/8969A61K36/9062A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 穆凤扬穆凤文穆凤鸣马凯张守良马宪东吴迪郭晓康邱飞井雪杰
Owner BOZHOU YONGGANG PIECES FACTORY
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