Chinese medicinal formulation for treating cardiovascular and cerebrovascular diseases and preparation process of products thereof

Abstract

The invention discloses a Chinese medicinal formulation for treating cardiovascular and cerebrovascular diseases and a preparation process of products thereof. The preparation process comprises the following steps of: decocting Chinese angelica, chuanxiong rhizome, safflower, salvia miltiorrhiza, American ginseng, notoginseng, tree peony bark, earthworms, leech and gradfly; filtering; adding Zygosaccharomyces bailii to the resulting filtrate and filter residues, standing to culture in appropriate temperature and humidity environments for 168 to 240 hours, and making oral liquids, oral tablets or capsules. The main indications of the product disclosed by the invention include cardiovascular and cerebrovascular diseases, hypertension and blood diseases, and the product is directly taken, has rapid onset of action, prevents the recurrence of diseases, is absorbed rapidly, has high curative effects, is sweet in taste, and cause no sequela or complication after administration. By applying microorganisms to Chinese medicines, the two special processes of solid fermentation and liquid fermentation are achieved, so as to eliminate the toxic and adverse effects of active pharmaceutical ingredients, provide convenience for storage and administration and not produce wastes or residues. Besides, the resources of raw materials are abundant, the production is simple and low in cost, and the product is applied to both therapy and health care.

Description

Technical field [0001] The invention relates to the technical field of Chinese medicine and traditional Chinese medicine, in particular to a traditional Chinese medicine formula for treating cardiovascular and cerebrovascular diseases and a product preparation process thereof. Background technique [0002] At present, about 3 million people die from cardiovascular disease every year in China, which accounts for 40% of all deaths. It is the number one killer of Chinese residents. Research predicts that the incidence of stroke among middle-aged men in China will increase by 42% in the next 10 years. , Women will increase by 13%, the incidence of coronary heart disease will increase by 26% for men, and 19% for women. In 2003, China’s direct medical expenses for cardiovascular disease was 130.117 billion yuan, accounting for the total medical expenses and total health expenses in China during the same period. The proportions were 22.65% and 19.74%, respectively; the top 3 diseases we...

AI Technical Summary

Problems solved by technology

[0002] At present, about 3 million people die of cardiovascular disease in my country every year, accounting for 40% of all causes of death. It is the number one killer of Chinese residents. Research predicts that the incidence of stroke among middle-aged men in my country will increase by 42% in the next 10 years , women will increase by 13%, and the incidence of coronary heart disease will increase by 26% for men and 19% for women. In 2003, the direct medical expenses of cardiovascular diseases in China were 130.117 billion yuan, accounting for 20% of China's total medical expenses and total health expenses during the same period. The proportions were 22.65% and 19.74% respectively; the top three diseases were hypertension (36.603 billion yuan), coronary heart disease (26.433 billion yuan), and cerebral infarction (23.732 billion yuan), which accounted for 20% of China's total medical expenses during the same period. The proportions are 6.37%, 4.60%, and 4.13%, respectively, and the main means of treating cardiovascular and cerebrovascular diseases at this stage are western medicine and western medicine surgery, which can quickly and effectively curb the disease, but there are strong toxic and side effects, repeated illness and even More serious, palliative but not permanent, expensive, sequelae or complications and many other problems;

[0003] Traditional Chinese medicine has unique advantages such as treating both symptoms and root causes, less toxic and side effects, and significant curative effect after long-term use; but there are defects such as primitive processing technology, relatively slow onset of treatment, difficult quantification of active ingredients, and bitter taste that is difficult to take for a long time; the reasons for this are, first of all, It is difficult to determine how much active ingredients in medicinal materials can be extracted. The active ingredients of boiled Chinese medicinal materials are often wrapped in the cell wall. The plant cell wall is a dense structure composed of cellulose, hemicellulose, pectin, lignin and other substances. Traditional Chinese medicine During the extraction process of active ingredients, it is necessary to overcome the double resistance of the cell wall and the intercellular substance; secondly, the process of re-digestion and decomposition cannot be controlled, because the decoction or Chinese patent medicine taken by the patient does not directly enter the blood to exert the drug effect, but passes through The gastrointestinal system of the human body needs to be re-digested and decomposed before it can be converted into the final effective active ingredient and enter the blood to exert the therapeutic effect of the drug;

[0004] Traditional Chinese medicine fermentation technology overcomes the defects of traditional Chinese medicine, and makes Chinese medicine have the advantages of being completely absorbed and utilized by the human body, quick curative effect, high efficacy, no toxic side effects, and adjustable taste of traditional Chinese medicine. It is a revolution to the traditional Chinese medicine industry; The ancients had already applied the microbial fermentation method to the preparation of traditional Chinese medicines years ago, such as Liushenqu and Banxiaqu, which are all medicines formed by solid fermentation of microorganisms (such as molds and yeasts) in nature. Uncontrollable, resulting in no better in-depth development of this technology; with the development of modern bioengineering technology, with the help of microorganisms, it is widely proposed to change the original medicinal properties of traditional Chinese medicine, improve the curative effect, and remove toxic and side effects, making traditional Chinese medicine fermentation a modern Hotspots in Chinese medicine research;

[0005] Apply microbial traditional Chinese medicine fermentation technology to the traditional Chinese medicine formula for the treatment of cardiovascular and cerebrovascular diseases, and create a product with fast absorption, high curative effect, quick effect, no repetition, low price, sweet taste, easy storage, convenient consumption, and no sequelae or complications after taking it. The finished product of traditional Chinese medicine has not yet been seen