Traditional Chinese medicine for treating primary osteoporosis and preparation method thereof

A technology for osteoporosis and primary disease, applied in the field of pharmacy, can solve the problems of unclear specific mechanism of action, poor long-term safety, and large side effects, and achieve the effect of no drug resistance, low cost, and small side effects

Inactive Publication Date: 2015-04-08
彭焱
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs have relatively large side effects, poor long-term safety, are expensive, or the specific mechanism of action is unclear, and cannot solve the inevitable problems such as restoring lost bone mass.

Method used

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  • Traditional Chinese medicine for treating primary osteoporosis and preparation method thereof

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preparation example Construction

[0048] Wherein, when the dosage form of described Chinese medicine is tablet, its preparation method comprises the following steps:

[0049]The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85 to 95% relative to 2 to 4 times the mass of the mixture, heat under reflux for 1 to 3 hours, extract, and filter to obtain a first extract The medicinal residues obtained by filtering are added with ethanol having an alcohol concentration of 85 to 95% relative to 1 to 2 times of the quality of the medicinal residues, refluxed for 1 to 3 hours, and extracted, and filtered to obtain the second extract; the first extraction The liquid and the second extract were combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0050] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer and pulverized for 1 to 2 ho...

Embodiment 1

[0058] Example 1 Tablet of the present invention

[0059] Take 290g of Rhizoma Angustifolia, 400g of Turtle Version, 160g of Thorn Dragon Tooth, 140g of Huangjing, 210g of Morinda officinalis, 240g of Red Salvia, 130g of Monascus, 160g of Laojunxu, 280g of E-ginseng, 220g of Shitou, and 190g of Kaami , oxtail 110g, deer tendon 280g, sunflower root 150g, cross meridian 230g, continuation 340g, tiger ginger 160g, seal kidney 280g, yam 250g and elk horn 330g;

[0060] Its preparation method comprises the following steps:

[0061] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% relative to 4 times the mass of the mixture, heat under reflux for 3 hours, extract, and filter to obtain a first extract; filter the obtained medicinal residues Then add 95% ethanol with an alcohol concentration of 2 times the mass of the medicinal residues, heat under reflux for 2 hours, extract, and filter to ...

Embodiment 2

[0064] Example 2 Syrup of the present invention

[0065] Take 260g of Rhizoma Angustifolia, 370g of Turtle Version, 180g of Thorn Longya, 120g of Huangjing, 230g of Morinda officinalis, 210g of Red Salvia, 120g of Monascus, 180g of Laojunxu, 270g of Esam, 230g of Shitou, and 160g of Camel , oxtail 110g, deer tendon 260g, sunflower root 130g, cross meridian mat 210g, continuation 330g, tiger ginger 190g, seal kidney 250g, yam 200g and elk horn 310g;

[0066] Its preparation method comprises the following steps:

[0067] In the first step, Radix Angustifolia, Turtle, Longya, Polygonatum, Morinda officinalis, Red Salvia and Monascus are mixed in the stated proportions with an alcohol concentration of 90% relative to 4 times the mass of the mixture obtained The ethanol was dissolved, heated and refluxed for 4 hours, extracted, and filtered to obtain the first filtrate; the filter residue was again dissolved in ethanol with an alcohol concentration of 95%, which was twice the mass...

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Abstract

The invention provides a traditional Chinese medicine for treating primary osteoporosis and a preparation method thereof. The traditional Chinese medicine is prepared from the following medicinal raw materials: cortex acanthopanacis giraldii, tortoise plastron, aralia elata, polygonatum kingianum, morinda officinalis, radix salviae miltiorrhizae, red yeast rice, unpleasant swallowwort herb, anthriscus sylvestris, drumfish, siberian nitraria fruit, meadow fescue, ligamentum cervi, franchet peashrub flower root, membranaceous beautyleaf root, radix dipsaci, tendrilleaf solomonseal rhizome, ursine seal testes and penis, Chinese yam and david deer horn. By utilizing the traditional Chinese medical theory, the traditional Chinese medicine has the advantages of small side effect, good curative effect, low cost, high cure rate, no drug resistance and convenience in taking when used for treating primary osteoporosis.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating primary osteoporosis and a preparation method. Background technique [0002] Osteoporosis (OP) is a disease characterized by osteopenia and structural deterioration of bone tissue (thinning, fracture, and reduction of trabecular bone in cancellous bone; porous and thinning of cortical bone). A systemic bone disease with increased fragility and increased risk of fracture. With the advent of an aging society, osteoporosis has gradually become a worldwide concern. There are two types of osteoporosis: primary and secondary. Primary osteoporosis includes postmenopausal osteoporosis (type I) and senile osteoporosis (type II). With the development of history and the advancement of science and technology, people's understanding of osteoporosis has gradually deepened. Common clinical symptoms of osteoporosis are bone and joint pain of diffe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P19/10A61K35/60A61K35/48A61K35/32A61K35/586
CPCA61K9/0095A61K9/2013A61K35/32A61K35/48A61K35/586A61K35/60A61K36/062A61K36/185A61K36/23A61K36/25A61K36/254A61K36/27A61K36/48A61K36/537A61K36/746A61K36/8945A61K36/896A61K36/8969A61K36/899A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 彭焱田风云
Owner 彭焱
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