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New application of rosuvastatin to treating coronary heart disease

A technology of rosuvastatin and coronary heart disease, applied in the field of medicine

Inactive Publication Date: 2015-04-22
李海云
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Domestic and foreign research on this aspect has not yet been reported

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  • New application of rosuvastatin to treating coronary heart disease
  • New application of rosuvastatin to treating coronary heart disease
  • New application of rosuvastatin to treating coronary heart disease

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Embodiment Construction

[0026] Apparently, according to the above content of the present invention, according to the general technical knowledge and conventional means in this field, without departing from the above basic technical idea of ​​the present invention, other various forms of modification, replacement or change can also be made.

[0027] The above-mentioned content of the present invention will be further described in detail below through specific implementation in the form of examples, but it should not be understood that the scope of the above-mentioned subject of the present invention is limited to the following examples. All technologies realized based on the above contents of the present invention belong to the scope of the present invention.

[0028] The use of rosuvastatin in the preparation of drugs for treating coronary heart disease is proved by the following experimental data.

[0029] Materials and Methods

[0030] 1.1 Materials

[0031]A total of 91 hospitalized patients wit...

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Abstract

The invention provides new application of rosuvastatin to treating the coronary heart disease. Tests prove that the large-dose rosuvastatin can obviously reduce the plasma Lp-PLA2 content; the plasma Lp-PLA2 content is obviously reduced along with increase of the dose; and the load-dosage rosuvastatin has the obvious effects on conducting forecasting and intervention treatment on occurrence and developing of the coronary heart disease. The load-dosage rosuvastatin can be used for treating the coronary heart disease.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a new application of rosuvastatin for treating coronary heart disease. Background technique [0002] Coronary heart disease is the abbreviation of coronary atherosclerotic heart disease. It refers to the heart disease caused by coronary atherosclerosis that blocks the lumen and the functional changes of coronary arteries, leading to myocardial ischemia and hypoxia. ischemic heart disease. Coronary heart disease is a common and frequently occurring disease in the Department of Cardiology, and it is a major killer of human health. Different kinds of inflammatory cells, inflammatory mediators and vascular endothelial cells play a key role in each stage of atherosclerotic plaque formation, progression to plaque instability and final rupture. At present, the inflammatory factors related to CHD that have been studied more at home and abroad include high-sensitivity C-reactive protei...

Claims

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Application Information

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IPC IPC(8): A61K31/505A61P9/10
CPCA61K31/505
Inventor 李海云逄锦聚
Owner 李海云