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Medical wound dressing with anti-infection function

An anti-infection and wound technology, applied in the fields of medical science, bandages, absorbent pads, etc., can solve problems such as the inability to effectively prevent the invasion of bacteria, the inability to solve the problem of antibiotic resistance, and the inability to achieve anti-infection effects, so as to promote the wound surface. Effects of healing, excellent biomechanical properties, good biocompatibility

Inactive Publication Date: 2015-05-06
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, gauze is an inert dressing, which has no obvious promotion effect on wound healing. When the dressing is soaked, pathogens are easy to infect the wound; and the maintenance cost of the dressing is high, the workload of dressing change is large, and it cannot effectively prevent the invasion of bacteria. Antibiotics Gauze is the addition of medicinal ingredients when gauze is used, which is also a common way to treat wounds, but it cannot solve the common problem of antibiotic resistance and cannot achieve the ideal anti-infection effect

Method used

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  • Medical wound dressing with anti-infection function
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Examples

Experimental program
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Effect test

Embodiment 1

[0033] This embodiment provides a medical wound dressing with anti-infection function, comprising a base layer 1, the base layer 1 is composed of cotton yarn fibers, and the affected side of the base layer 1 is provided with magnesium alloy fibers 2, and the magnesium alloy fibers 2 can be prepared in various forms. These forms are arranged on the base layer and can be arranged vertically such as figure 1 A, can also be arranged obliquely, such as figure 1 As shown in B, the magnesium alloy fiber 2 can also be woven into a magnesium alloy fiber mesh, such as figure 1 C shown. The magnesium alloy fiber 2 contains 1 wt % of silver and the rest of magnesium, and the diameter of the magnesium alloy fiber 2 is 800 μm.

[0034] Biosecurity:

[0035] Biological evaluation was carried out according to the experimental method described in GB / T16886. Experimental results show that the medical wound dressing with anti-infection function provided in this example has no obvious cytotox...

Embodiment 2

[0042] This embodiment provides a medical wound dressing with anti-infection function, comprising a base layer 1, the base layer 1 is composed of cotton yarn fibers, and the affected side of the base layer 1 is provided with magnesium alloy fibers 2, and the magnesium alloy fibers 2 can be prepared in various forms. These forms are arranged on the base layer and can be arranged vertically such as figure 1 A, can also be arranged obliquely, such as figure 1 As shown in B, the magnesium alloy fiber 2 can also be woven into a magnesium alloy fiber mesh, such as figure 1 C shown. The magnesium alloy fiber 2 contains 2 wt % of silver and the balance of magnesium, and the diameter of the magnesium alloy fiber 2 is 1000 μm. .

[0043] Biosecurity:

[0044] Biological evaluation was carried out according to the experimental method described in GB / T16886. Experimental results show that the medical wound dressing with anti-infection function provided in this example has no obvious ...

Embodiment 3

[0051] This embodiment provides a medical wound dressing with anti-infection function, comprising a base layer 1, the base layer 1 is composed of cotton yarn fibers, and the affected side of the base layer 1 is provided with magnesium alloy fibers 2, and the magnesium alloy fibers 2 can be prepared in various forms. These forms are arranged on the base layer and can be arranged vertically such as figure 1 A, can also be arranged obliquely, such as figure 1 As shown in B, the magnesium alloy fiber 2 can also be woven into a magnesium alloy fiber mesh, such as figure 1 C shown. The magnesium alloy fiber 2 contains 0.25wt% copper and the rest magnesium, and the diameter of the magnesium alloy fiber 2 is 700 μm. .

[0052] Biosecurity:

[0053] Biological evaluation was carried out according to the experimental method described in GB / T16886. Experimental results show that the medical wound dressing with anti-infection function provided in this example has no obvious cytotoxic...

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Abstract

The invention provides a medical wound dressing with an anti-infection function. The medical wound dressing includes a substrate layer, the affected side surface of the substrate layer is provided with magnesium alloy fibers or a magnesium alloy fiber net formed by braiding the magnesium alloy fibers, and the content of magnesium in the magnesium alloy fibers is more than or equal to 90wt%. In a preferred embodiment, the magnesium alloy fibers are copper-containing magnesium alloy fibers or silver-containing magnesium alloy fibers. The medical wound dressing with an anti-infection function has good biocompatibility, good biodegradability and ideal anti-infection function, also has wound healing promotion, adhesion prevention and other auxiliary performances, can be used to treat different wounds, such as incised wounds, burns, electrochemical injuries and surgical incision, can protect the wounds and prevent and treat wound infection, has good biomechanical performances and permeability, and has important clinical application values.

Description

technical field [0001] The invention relates to the field of medical biomaterials, in particular to a medical wound dressing with anti-infection function. Background technique [0002] Different types of skin wounds will be caused by external injury factors such as surgery, external force, heat, electric current, chemical substances, low temperature, and internal factors such as local blood supply disorders, resulting in damage to skin integrity and a certain amount of normal skin. The loss of tissue, reconstruction or restoration of skin function is the ultimate goal of clinical wound treatment. Before reaching this goal, researchers have developed different types of wound coverings, that is, dressings, so that they can temporarily play part of the skin barrier function and provide An environment conducive to wound healing, awaiting epithelialization of the wound or transition to rebuilding the permanent skin barrier. With the in-depth study of the pathophysiology of the w...

Claims

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Application Information

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IPC IPC(8): A61L15/18A61L15/44
Inventor 曲新华戴尅戎李扬
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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