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Anti-influenza virus pharmaceutical composition

An anti-influenza virus and composition technology, applied in the field of pharmaceutical compositions, can solve the problems such as the lack of establishment of antibacterial and antiviral pharmacodynamics research and the like

Inactive Publication Date: 2015-05-13
YABAO PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many studies on the chemical components, pharmacological effects, and extraction techniques of Forsythia. For example, patent 200910050773.X discloses the use of forsythiaside A in the preparation of drugs for the treatment of influenza. "Study on the Effect of Forsythin on Gene Expression" discussed the effect of forsythin on the expression of influenza A virus nucleoprotein (NP) gene after transfection. Pharmacodynamic research, no antibacterial and antiviral pharmacodynamic research after the ratio of the two ingredients has been established

Method used

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  • Anti-influenza virus pharmaceutical composition
  • Anti-influenza virus pharmaceutical composition
  • Anti-influenza virus pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Embodiment 1 injection

[0061] Take 200g of forsythin and 200g of forsythiaside A, add conventional excipients, and make injection according to the conventional process.

Embodiment 2

[0062] Example 2 tablet

[0063] Take 200g of forsythin and 400g of forsythin A, add conventional excipients, and make tablets according to the conventional process.

Embodiment 3

[0064] Embodiment 3 capsules

[0065] Take 400 g of forsythin and 200 g of forsythiaside A, add conventional auxiliary materials, and make capsules according to conventional processes.

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PUM

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Abstract

The invention discloses an anti-influenza virus pharmaceutical composition, the ratio of raw material medicines of forsythin to forsythiaside A is 0.5-4:0.5-10, the forsythin and the forsythiaside A are prepared by a conventional extraction method, and the purity is at least 80% above. The pharmaceutical composition is added with conventional accessories, and prepared into various pharmaceutically acceptable dosage forms according to the conventional process, the pharmaceutically acceptable dosage forms include but not limited to, injections, tablets, capsules, granules, pills and oral liquid preparations. The medicine efficacy of the two medicines is significantly improved after combination of the two medicines by effective dose of compatibility test of the forsythin and the forsythiaside A.

Description

field of invention [0001] The invention relates to a pharmaceutical composition, in particular to an anti-influenza virus pharmaceutical composition. Background technique [0002] Forsythia is a deciduous shrub belonging to the family Oleaceae Forsythia. It is a commonly used medicinal material. Traditionally, the fruit is used as medicine. Some researchers have also studied the chemical components of Forsythia leaves. Good consistency. Forsythin and forsythiaside A are the index components for quality control of forsythia. Forsythin has good antibacterial, blood fat-lowering and weight-loss effects; forsythiaside has good anti-virus and antioxidant effects, has inhibitory effects on Staphylococcus aureus and other pathogenic bacteria, and can also inhibit diphosphate Esterases, fungi, and reactive oxygen species. [0003] At present, there are many studies on the chemical components, pharmacological effects, and extraction techniques of Forsythia. For example, patent 200...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61P31/16A61K31/7032
Inventor 禹玉洪杨芮平任武贤
Owner YABAO PHARMA GRP CO LTD