A kind of plant polysaccharide cleaning liquid

A technology of plant polysaccharides and cleaning fluids, applied in the field of medicine, to achieve good biological safety, meet clinical application requirements, and long-lasting effects

Active Publication Date: 2018-03-30
河北柯瑞生物医药有限公司
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] So far there is no report on the use of sodium carboxymethylcellulose in intestinal cleansing

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of plant polysaccharide cleaning liquid
  • A kind of plant polysaccharide cleaning liquid
  • A kind of plant polysaccharide cleaning liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～6

[0023] Using sodium carboxymethyl cellulose with different mass percentages and degrees of substitution as raw materials, the process of preparing plant polysaccharide cleaning solution: weigh sodium carboxymethyl cellulose as shown in Table 1, and mix carboxymethyl cellulose with stirring. Sodium cellulose is dissolved in water for injection. After fully dissolving, add 9g of sodium chloride, 0.811g of potassium dihydrogen phosphate, and 0.189g of sodium hydroxide, fully stir and dissolve, and finally make up to 1000ml with water for injection, measure the pH value, and filter , the filtrate is filled and sealed, and steam sterilized at 121°C for 30 minutes.

[0024] Table 1 Determination of parameters of sodium carboxymethyl cellulose

[0025] .

Embodiment 7～9

[0027] The preparation process of further adding carboxymethyl chitosan plant polysaccharide cleaning solution: take by weighing 5 g of sodium carboxymethyl cellulose with a degree of substitution of 0.62, and dissolve sodium carboxymethyl cellulose in water for injection under stirring, and wait until fully After dissolving, add 9g of sodium chloride, 0.811g of potassium dihydrogen phosphate, 0.189g of sodium hydroxide, carboxymethyl chitosan, fully stir to dissolve, and finally make up to 1000ml with water for injection, measure the pH value, filter, and fill the filtrate Seal; sterilize by steam at 121°C for 30 minutes, ready to serve. The amount of carboxymethyl chitosan added is shown in Table 2.

[0028] Table 2 Addition amount of carboxymethyl chitosan

[0029]

Embodiment 10～13

[0031] The preparation process of the plant polysaccharide cleaning liquid further adding magnesium chloride: Weigh 5 g of sodium carboxymethyl cellulose with a degree of substitution of 0.62, and dissolve sodium carboxymethyl cellulose in water for injection under stirring. After fully dissolving, add Sodium chloride 9g, potassium dihydrogen phosphate 0.811g, sodium hydroxide 0.189g, magnesium chloride and carboxymethyl chitosan 4g, fully stir to dissolve, and finally make up to 1000ml with water for injection, measure the pH value, filter, fill and seal the filtrate ; 121 ℃ steam sterilization for 30 minutes, that is. The amount of magnesium chloride added is shown in Table 3.

[0032] Table 3 The amount of magnesium chloride added

[0033]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
degree of substitutionaaaaaaaaaa
Login to view more

Abstract

The invention relates to a plant polysaccharide cleaning solution mainly composed of sodium carboxymethyl cellulose for intestinal cleaning, which comprises the following components: sodium carboxymethyl cellulose with a mass percentage of 0.1% to 2% , 0.7% to 1.2% by mass of sodium chloride, 0.01% to 0.1% by mass of pH value buffer substances and optional magnesium chloride, mannitol, phenolphthalein and carboxymethyl chitosan, the rest The amount is water for injection, wherein the mass percentage of magnesium chloride is 0.1% to 5%, the mass percentage of mannitol is 1% to 10%, the mass percentage of phenolphthalein is 0.01% to 0.1%, and the mass percentage of carboxymethyl chitosan The percentage content is 0.1%-0.4%, and the pH range of the plant polysaccharide cleaning solution is 6.5-7.8. The plant polysaccharide cleaning solution provided by the invention has good cleaning effect, no adverse reaction, and the cleaning solution is stable and difficult to degrade.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a cleaning solution mainly composed of sodium carboxymethyl cellulose for intestinal cleaning. Background technique [0002] Before colonoscopy, enema X-ray examination or colon surgery, oral medication or enema is generally used for intestinal cleansing. Oral medicine has a special smell and salty taste, accompanied by severe diarrhea, which is unbearable for patients. Enema is generally to inject normal saline or glycerin into the intestine from the anus to soften the stool and facilitate the excretion of stool. However, the effect of normal saline is slow and the cleaning is not thorough. Hypertonic solutions such as glycerin have many side effects, which can easily cause abdominal pain, bloating, Even cause serious adverse reactions such as dehydration. [0003] The raw material of sodium carboxymethyl cellulose is natural plant fiber, which is safe and reliabl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/717A61P1/10
Inventor 李素哲董科刘媞刘俊英李璟
Owner 河北柯瑞生物医药有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap