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A kind of purslane seed oil composite soft capsule and its preparation and application in enhancing immunity

A technology for compounding soft capsules and purslane seeds is applied in the directions of capsule delivery, drug combination, and medical preparations containing active ingredients, which can solve problems such as increasing efficacy and achieve the effect of high nutritional value.

Active Publication Date: 2018-04-27
新疆源森农业开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the continuous development of soft capsule technology, there has been research on compound soft capsules, that is, two or more active ingredients are wrapped and matched with capsule shells in order to achieve a synergistic effect. The compatibility between active ingredients has a synergistic effect. Or the combination of multiple ingredients can significantly increase the efficacy of one or several aspects of the product, and can achieve the multi-faceted goal of increasing efficiency and reducing costs. At present, there is no combination of purslane seed oil and purslane whole grass alcohol Preparation of Portulaca oleracea Seed Oil Composite Soft Capsules by Compatibility of Extracts and Related Application Reports

Method used

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  • A kind of purslane seed oil composite soft capsule and its preparation and application in enhancing immunity
  • A kind of purslane seed oil composite soft capsule and its preparation and application in enhancing immunity
  • A kind of purslane seed oil composite soft capsule and its preparation and application in enhancing immunity

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Experimental program
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Effect test

Embodiment 1

[0055] Embodiment one: the preparation of purslane seed oil composite soft capsule

[0056] The present invention specifically provides a composite soft capsule of purslane seed oil, which is specifically prepared through the following process, % is calculated by weight percentage, and the specific preparation method steps are as follows:

[0057] (1) Purslane seed oil passed through supercritical CO 2 Extracted or prepared by common extraction methods.

[0058] (2) Preparation of the alcoholic extract of purslane whole herb: crush the whole purslane herb through a 40-mesh to 80-mesh sieve, and use 10 times the amount of 60%-80% ethanol for reflux extraction 2-3 times, each time After 1 hour, the extracts were combined several times, concentrated by low-temperature rotary evaporation until the smell of ethanol disappeared, and then freeze-dried to prepare the ethanol extract of purslane whole herb.

[0059] (3) Suspension preparation: mix the purslane seed oil and beeswax pr...

Embodiment 2

[0062] Embodiment two: the preparation of purslane seed oil composite soft capsule

[0063] Portulaca oleracea seed oil compound soft capsules are specifically prepared through the following process: %according to weight percentage, purslane seed oil is passed through supercritical CO 2 Extracted or prepared by common extraction methods; the whole herb of purslane is crushed through a 40-mesh sieve, refluxed with 10 times the amount of 60% ethanol for 2 times, each time for 1 hour, the 2 times of extracts are combined, and low-temperature rotary evaporation is carried out. Concentrate until the ethanol smell disappears, freeze-dry, and prepare the ethanol extract of purslane whole herb; mix the prepared purslane seed oil and beeswax according to the weight ratio of 1:2, and heat to 60°C to make The beeswax is completely melted, then stirred and cooled to below 35°C, added soybean lecithin, stirred evenly, and finally added the prepared ethanol extract of purslane whole herb, s...

Embodiment 3

[0064] Embodiment three: the preparation of purslane seed oil composite soft capsule

[0065] Portulaca oleracea seed oil compound soft capsules are specifically prepared through the following process: %according to weight percentage, purslane seed oil is passed through supercritical CO 2Extracted or prepared by common extraction methods; crush the whole purslane herb through an 80-mesh sieve, use 10 times the amount of 80% ethanol to carry out reflux extraction for 3 times, each time for 1 hour, combine the extracts for 3 times, and carry out low-temperature rotary evaporation Concentrate until the ethanol smell disappears, freeze-dry, and prepare the ethanol extract of purslane whole herb; mix the prepared purslane seed oil and beeswax according to the weight ratio of 1:2, and heat to 70°C to make The beeswax is completely melted, then stirred and cooled to below 35°C, added soybean lecithin, stirred evenly, and finally added the prepared ethanol extract of purslane whole he...

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Abstract

The invention discloses a purslane seed oil compound soft capsule as well as a preparation method and application thereof in enhancing immunity. The purslane seed oil compound soft capsule contains the following components in percentage by weight: 90-93% of a mixture containing purslane whole herb alcohol extract and purslane seed oil, 4.5-6.5% of beeswax and 2-4% of soybean lecithin, wherein the weight ratio of the purslane whole herb alcohol extract to the purslane seed oil in the mixture containing the purslane whole herb alcohol extract and the purslane seed oil is 1:2; the purslane seed oil and the purslane whole herb alcohol extract are combined together to prepare the purslane seed oil compound soft capsule for the first time, and the antioxidant activities and antibacterial activities inside and outside a sample before and after combination are used for performing test evaluation on the compatibility effect of the purslane seed oil and the purslane whole herb alcohol extract; and the obtained purslane seed oil compound soft capsule has a good and significant technical effect in enhancing immunity, and has a wide application value.

Description

technical field [0001] The invention relates to the technical field of soft capsules prepared by biotechnology. Specifically, the present invention relates to a purslane seed oil composite soft capsule and the technical field of its preparation and application in enhancing immunity. Background technique [0002] purslane( Portulaca oleracea L. ), also known as Longevity Vegetable and An Lecao, is an annual succulent herb of the family Portulaca oleracea. Purslane is one of the wild plants with the same origin of medicine and food identified by the Ministry of Health. Purslane and its seeds are rich in polyunsaturated fatty acids. At present, there are many studies on purslane flavonoids, alkaloids, polysaccharides, etc., but there are few reports on the research on purslane seed oil, which makes most purslane seeds undeveloped and utilized, resulting in waste of resources. Purslane seed oil is a natural health-care vegetable oil rich in linolenic acid and linoleic acid. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61K9/48A61P37/04A61P39/06A61P31/04
Inventor 敬思群童莲花蔡远强
Owner 新疆源森农业开发有限公司