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Application of giant salamander mucus in preparation of bleeding-stopping material

A technology of giant salamander mucus and hemostatic materials, which is applied in medical science, absorbent pads, bandages, etc., can solve the problem of low utilization rate, and achieve the effect of natural ingredients, good safety, and good hemostatic effect

Inactive Publication Date: 2015-07-08
CHONGQING KUIXU BIOLOGICAL SCI & TECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the production of giant salamander mucus is very abundant, it can be collected repeatedly in large quantities, and its utilization rate is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The method for preparing a hemostatic material from the giant salamander mucus comprises the following steps: placing the petri dish from which the giant salamander mucus is collected at -80°C overnight to freeze it into a solid, and then using a vacuum freeze dryer to freeze at a vacuum degree of 19pa and a temperature of -50°C Vacuum-dry for 48 hours; then mash the lyophilized giant salamander mucus and put it in a low-temperature ultrafine pulverizer to pulverize to 300 mesh, and finally use 5×10 4 Gy dose of 60Co gamma ray irradiation sterilization to obtain hemostatic material, aseptic packaging for future use. Among them, the temperature of low-temperature pulverization should be lower than 37°C, and the superfine pulverization effect of adding liquid nitrogen is the best.

Embodiment 2

[0019] The method for preparing a hemostatic material from the giant salamander mucus comprises the following steps: placing the petri dish for collecting the giant salamander mucus at -20°C overnight to freeze it into a solid, and then using a vacuum freeze dryer to freeze at a vacuum degree of 10 Pa and a temperature of -70°C Vacuum-dry for 56 hours; then mash the lyophilized giant salamander mucus and put it in a low-temperature ultrafine pulverizer to pulverize to 500 mesh, and finally use 2×10 4 Gy dose of 60Co gamma ray irradiation sterilization to obtain hemostatic material, aseptic packaging for future use. Among them, the temperature of low-temperature pulverization should be lower than 37°C, and the superfine pulverization effect of adding liquid nitrogen is the best.

Embodiment 3

[0021] The method for preparing a hemostatic material from the giant salamander mucus comprises the following steps: directly placing the petri dish for collecting the giant salamander mucus in a vacuum drying oven, drying the dried giant salamander mucus under vacuum for 48 hours at 37° C., crushing the dried giant salamander mucus and placing it in a low-temperature ultrafine pulverizer Crush to 1000 mesh, and finally use 2×10 4 Gy dose of 60Co gamma ray irradiation sterilization, to obtain hemostatic material, aseptic packaging for future use. Among them, the temperature of low-temperature pulverization should be lower than 37°C, and the superfine pulverization effect of adding liquid nitrogen is the best.

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Abstract

The invention discloses an application of giant salamander mucus in preparation of a bleeding-stopping material. An injured wound can be sealed by utilizing adhesion property of the giant salamander mucus, and therefore, the giant salamander mucus can be used as the bleeding-stopping material. The bleeding-stopping material is obtained from giant salamander mucus, is a purely natural component, good in safety, good in bleeding-stopping effect and wide in application prospect.

Description

technical field [0001] The invention belongs to the field of biological materials, and in particular relates to the application of giant salamander mucus in preparing hemostatic materials. Background technique [0002] The giant salamander, commonly known as the giant salamander, belongs to the family Cryptogillidae of the order Amphibians, and includes 2 genera and 3 species, namely the genus Giant salamander and the genus Cryptogill. Among them, the genus Giant salamander can be divided into the Japanese giant salamander and the Chinese giant salamander. It is the largest and most precious in the world. Amphibians have been included in the endangered species protection list by the United Nations, and they are national second-class protected aquatic wild animals. Giant salamander meat is tender and delicious, contains high-quality protein, rich in amino acids and trace elements, and has extremely high nutritional value. It is known as "ginseng in water" and "soft gold". Wh...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/42
Inventor 商海涛王莹陈兵苟强魏泓邢孟秋葛良鹏周明辉
Owner CHONGQING KUIXU BIOLOGICAL SCI & TECH
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