Production technology of preparing orally taken solid preparation

Abstract

The invention relates to a production technology of preparing an orally taken solid preparation. The production technology comprises the following steps: firstly, performing pelletization, and using a pelletizer for performing pelletization toraw materials of the orally taken preparation so as to obtain granular powder; secondly, performing mixing, and using a material mixing machine to uniformly mix the raw material powder of an orally taken preparation and auxiliary materials; then using a sheeter for performing tabletting treatment tothe mixed powder; then performing aluminum plastic packaging treatment on tablets; finally, performing outer packaging treatment. The material mixing machine comprises a V-shaped material mixing bin, feed openings are symmetrically formed in the two end parts of the V-shaped material mixing bin, a discharge opening is formed in the bottom of the V-shaped material mixing bin, through two symmetrical rotating shafts, the outer side wall of the V-shaped material mixing bin is connected with fixing seats which are symmetrically arranged, the rotating shafts are controlled by a motor arranged in the fixing seats, the feed openings and the discharge opening are all provided with assorted sealing covers, and a helical interception board of which the axial direction is the same as the axial directions of the rotating shafts is arranged in the V-shaped material mixing bin. The production technology disclosed by the invention solves the problem of lower uniformity when powdery raw material medicinesare uniformly mixedthrough the conventional material mixing machine.

Description

technical field [0001] The invention relates to the field of mixers, in particular to a production process for preparing oral solid preparations. Background technique [0002] In the production line of pharmaceutical preparations, the mixer has become an indispensable processing equipment. The mixer is a mechanical device that uses mechanical force and gravity to evenly mix two or more materials, usually including vertical or horizontal, and the indispensable structure of the mixer is used to hold The mixing bin of the raw materials and the stirring rod used for stirring the mixed raw materials, the mixing bin and the stirring rod can be rotated simultaneously under the drive of the motor, and the mixing of the mixed raw materials in the mixing bin can be realized through the rotation of the mixing bin and the stirring rod. uniform. This type of mixer is not only widely used in the biopharmaceutical preparation industry, but also in different industries such as food proces...

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a production process for preparing oral solid preparations, so as to overcome the problem of low uniformity of powder raw medicine mixing by existing mixers

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