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Sodium management system for hemodialysis

一种管理系统、透析液的技术，应用在受控添加机构领域，能够解决吸附材料耗尽、很难预测透析液、钠浓度变化等问题

Active Publication Date: 2015-10-21
MEDTRONIC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, it is difficult to predict what will happen to the sodium concentration in the dialysate during hemodialysis
Expensive sorbent materials are depleted and complex management systems are required to monitor the sodium concentration of the dialysate effluent from the sorbent system

Method used

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  • Sodium management system for hemodialysis
  • Sodium management system for hemodialysis
  • Sodium management system for hemodialysis

Examples

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example

[0369] Electrodialysis for Sodium Management

[0370] To remove sodium generated from an ion-exchange-based dialysate regeneration system, laboratory-scale electrodialysis experiments were performed to determine the requirements.

[0371] Assuming a 5-day / week hemodialysis schedule, a 70-kg patient produces BUN at a rate of 63 g / week. The amount of urea that will be removed from the dialysate per time period will be 470 mmoles. Additionally, dialysate regeneration is assumed to be performed using a sorbent system similar to REDY. 470 mmoles of urea will generate 940 mmoles of ammonia which will displace up to 940 mmoles of sodium ions during the ion exchange reaction of the zirconium phosphate layer. Likewise, assume that the average rate of sodium production will be 5 mmol / min over a period of 3 hours. Therefore, to keep the dialysate sodium concentration constant, it is desirable to have an electrodialysis system that removes sodium at a rate of 5 mmol / min.

[0372] For ...

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Abstract

Systems and methods for managing the sodium concentration of a dialysate fluid during hemodialysis therapy and adjusting sodium concentration using a sodium management system to generate a sodium-modified fluid. The systems and methods also provide a mechanism for controlled addition of sodium ions to the dialysate to generate a predetermined total sodium concentration in a dialysate.

Description

[0001] cross reference [0002] This application claims priority to US Patent Application Serial No. 13 / 757,794, filed February 2, 2013, which is hereby incorporated by reference in its entirety. field of invention [0003] The present invention relates to a system for managing the sodium concentration in the dialysate fluid during hemodialysis treatment. The present invention provides a mechanism for regulating sodium concentration using a sodium management system to generate a sodium modified fluid. The present invention also provides a controlled addition mechanism for adding sodium ions to the dialysate to create a predetermined total sodium concentration in the dialysate. Background technique [0004] During hemodialysis, the sodium concentration in the dialysate plays an important role in the patient's recovery outcome. In addition, hemodialysis of patients with specific sodium ion concentrations in the dialysate may affect the development of hypotension, the preven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/14
CPCA61M1/287A61M1/1656A61M1/1696A61M1/3472A61M1/3406A61M1/1666A61M1/1668A61M1/3479A61M1/3486
Inventor 布莱恩特·J·普迪尔马丁·T·格伯大卫·B·卢拉托马斯·E·迈耶
Owner MEDTRONIC INC
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