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Plaster used for treating infantile diarrhea and preparation method thereof

A technology for infant diarrhea and plasters, which can be used in pharmaceutical formulas, medical preparations containing active ingredients, and medical raw materials derived from arthropods, etc. It can solve problems such as liver and kidney damage, increased stool frequency, and poor permeability of plasters , to achieve the effect of strong penetration and infiltration into subcutaneous tissue, high content of active ingredients, and good healing prospects

Inactive Publication Date: 2015-12-02
马士远
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main clinical manifestations are increased stool frequency, loose stools, and water-electrolyte disorders. If not treated in time, severe water-electrolyte disorders may endanger the lives of children. Currently, oral drugs, intramuscular injections or infusions are usually used for treatment of infantile diarrhea. The drug is more irritating to the gastrointestinal tract, which is unbearable for infants and young children. Intramuscular injection and infusion will cause varying degrees of damage to the liver and kidney.
Some existing medicines for the treatment of infantile diarrhea are also not satisfactory. The main reasons are: the selection of raw materials is not precise enough, it is difficult for patients to persist in long-term medication, the content of active ingredients in plasters is low, and the permeability of plasters is not good.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Weighing: gallnut 6g, prickly ash 7g, clove 10g, evodia 4g, woody 8g, fried Atractylodes 6g, atractylodes 7g, cinnamon 2g, hawthorn 5g, edible vinegar 6g, azone 2g, rosin 10g, hot melt glue 20g.

[0027] The preparation method is:

[0028] Use the hot melt adhesive and rosin used for plaster as the base of the ointment, and mix them evenly in advance; soak Chinese gallnut, pepper, clove, evodia, woody, fried Atractylodes macrocephala, atractylodes rhizome, cinnamon, and hawthorn in water for 2-3 days, and decoct them in water 2-3 times, decocting each time to remove the juice and remove the residue, then combine the obtained concoctions, then add edible vinegar, mix and concentrate to obtain medicinal material extract; heat and melt the ointment base, then add medicinal material extract and Azone, after mixing and cooling to solid, obtains plaster; heat and melt the ointment matrix, cool to 65-70°C, take 9-10 grams of ointment on the beach backing material, use desensit...

Embodiment 2

[0031] Weighing: gallnut 7g, pepper 8g, clove 12g, evodia 5g, woody 9g, fried Atractylodes 8g, atractylodes 8g, cinnamon 6g, hawthorn 10g, edible vinegar 8g, azone 3g, rosin 15g, hot melt glue 25g.

[0032] The preparation method is:

[0033] Use the hot melt adhesive and rosin used for plaster as the base of the ointment, and mix them evenly in advance; soak Chinese gallnut, pepper, clove, evodia, woody, fried Atractylodes macrocephala, atractylodes rhizome, cinnamon, and hawthorn in water for 2-3 days, and decoct them in water 2-3 times, decocting each time to remove the juice and remove the residue, then combine the obtained concoctions, then add edible vinegar, mix and concentrate to obtain medicinal material extract; heat and melt the ointment base, then add medicinal material extract and Azone, after mixing and cooling to solid, obtains plaster; heat and melt the ointment matrix, cool to 65-70°C, take 9-10 grams of ointment on the beach backing material, use desensitizin...

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PUM

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Abstract

The invention discloses a plaster used for treating infantile diarrhea and relates to the technical field of plaster preparation. The plaster is prepared with the following active pharmaceutical ingredients including, by weight, 6-8 parts of gallnut, 7-10 parts of pepper, 10-15 parts of clove, 4-6 parts of evodia fruit, 8-10 parts of costus root, 6-10 parts of fried white atractylodes rhizome, 7-10 parts of Chinese atractylodes rhizome, 2-10 parts of cinnamon, 5-15 parts of hawthorn, 6-10 parts of edible vinegar, 2-5 parts of azone, 10-20 parts of rosin and 20-30 parts of hot melt adhesive. The plaster has the advantages of accurate medication and high effective ingredient content, is directly pasted at a belly button, has high capability of permeating and infiltrating into subcutaneous tissue, realizes effects of ventilating, eliminating dampness and tonifying spleen, relieving abdominal distension and regulating qi and blood and has good healing prospect for infantile diarrhea.

Description

technical field [0001] The invention relates to the technical field of plaster preparation, in particular to a plaster for treating infantile diarrhea and a preparation method thereof. Background technique [0002] It is an acute gastrointestinal dysfunction in infants and young children, a syndrome mainly characterized by diarrhea and vomiting, with the highest incidence in summer and autumn. The pathogenic factors of this disease are divided into three aspects: constitution, infection and digestive disorder. The main clinical manifestations are increased stool frequency, loose stools, and water-electrolyte disorders. If not treated in time, severe water-electrolyte disorders may endanger the lives of children. Currently, oral drugs, intramuscular injections or infusions are usually used for treatment of infantile diarrhea. The medicine is more irritating to the gastrointestinal tract, which is unbearable for infants and young children. Intramuscular injection and infusion...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61K9/70A61P1/12A61K35/64
Inventor 马士远
Owner 马士远