Liver-benefiting dropping pill prepared from total neterosides of swertia mileensis, and its preparing method

A technology of Qingyedan ​​and Kangdiwan, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, and unknown raw materials, etc., can solve the problem of first-pass bioavailability of the liver and intestines, which is not conducive to improving the ability of patients to seek medical treatment, and is not conducive to overall health Level and other issues, to achieve the effects of labor protection and environmental protection, improve bioavailability, and ensure the quality of drugs

Inactive Publication Date: 2005-12-21
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

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Embodiment Construction

[0027] Several specific examples are now given to further illustrate the preparation method of Ligankang dripping pills of the present invention.

[0028] [The first group: single matrix test]

[0029] 1. Raw material: total glycosides of green leaf gall (a medicinal extract containing active ingredients of Chinese medicine green leaf gall);

[0030] 2. Matrix: polyethylene glycol 1000 Polyethylene glycol 4000 Polyethylene glycol 6000 Polyethylene glycol 10000 Polyethylene glycol 20000 , Span 40, polyoxy 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0031] 3. Mixing ratio: in g or kg, in parts by weight, the drug extract (total gall glycosides of green leaf): matrix=1:1~1:9;

[0032] 4. According to the process given in [Preparation Method] 4-7, Ligankang dripping pills of different specifications can be obtained.

[0033] [test results]

[0034] Test 1: In order to observe the difference in the quality of the Ligankang ...

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PUM

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Abstract

The present invention discloses a Chinese medicine composition with the actions of soothing liver and strengthening spleen for curing hepatitis. Said Chinese medicine composition can be made into oral preparation Ligankang dripping pills, and is made up by using Chinese medicine extract swertia mileensis total glucoside as raw material and medicinal carrier as matrix through a certain preparation process.

Description

Technical field [0001] The invention relates to a pharmaceutical composition with the functions of relaxing the liver and strengthening the spleen for treating hepatitis, and particularly relates to an oral preparation of the pharmaceutical composition prepared from the total glioside of Chinese medicine extract. Background technique [0002] Ligankang tablets are prepared according to the preparation method given in the national drug standard WS-10997(ZD-0997)-2002. It is an oral tablet that has the function of relaxing the liver and strengthening the spleen and is used to treat hepatitis. It has been verified that the curative effect is definite, and it is a common medicine used clinically and at home to treat the above-mentioned diseases. [0003] The following is the formula and process and brief description given in the drug standard WS-10997(ZD-0997)-2002: [0004] Prescription: 76g (sugar-coated tablets) or 152g (film-coated tablets), starch 118g (sugar-coated tablets) or ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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