Extracting method and application of plant composite containing mycelia of cultured cordyceps sinensis

A technology of Cordyceps mycelium and extraction method, which is applied in the directions of drug combination, medical preparations containing active ingredients, plant raw materials, etc.

Inactive Publication Date: 2015-12-09
南京多宝生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Cordyceps mycelium. However, the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient. Taking it seriously affects the clinical application of this product

Method used

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  • Extracting method and application of plant composite containing mycelia of cultured cordyceps sinensis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 100g of Cordyceps mycelium, 60g of Zhulingcao, 80g of Ishimichuan, and 160g of Pennisetum, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice , 4-8 minutes each time, combine the extracts, concentrate, add to the D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain The microwave extract is prepared into tablets with conventional excipients, 0.4g per tablet.

Embodiment 2

[0016] Take 100g of Cordyceps mycelium, 60g of Zhulingcao, 80g of Ishimichuan, and 160g of Pennisetum, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice , 4-8 minutes each time, combine the extracts, concentrate, add to the D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain The microwave extract is prepared into capsules with conventional auxiliary materials.

Embodiment 3

[0018] Take 100g of Cordyceps mycelium, 60g of Zhulingcao, 80g of Ishimichuan, and 160g of Pennisetum, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, and the extraction is performed twice , 4-8 minutes each time, combine the extracts, concentrate, add to the D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry to obtain The microwave extract is prepared into granules with conventional auxiliary materials.

[0019] Juling grass is the whole plant of Gentiana apiata N.E.Brown, a plant of the Gentianaceae Gentiana. Harvested in summer and sun-dried. Regulating menstruation and promoting blood circulation, clearing away heat and improving eyesight, diuresis. For irregular menstruation, dysmenorrhea, dizziness, insomnia, dysuria, gonorrhea, metrorrhagia, leucorrhea, dysent...

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Abstract

The invention provides an extracting method of a plant composite containing mycelia of cultured cordyceps sinensis. The plant composite is prepared from the raw material herbs of 100 g of mycelia of cultured cordyceps sinensis, 60 g of gentiana apiata, 80 g of salvia chinensis and 160 g of Chinese pennisetum. The plant composite is prepared by the adoption of the microwave extracting method, in this way, the content is greatly increased, and the usage amount is reduced. The invention further provides an application of the plant composite containing the mycelia of cultured cordyceps sinensis in preparation of medicine for restraining C57BL / 6 mice fibrosarcoma S180 cell proliferation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing Cordyceps mycelium. Background technique [0002] The plant composition containing Cordyceps mycelium is made from 100g of Cordyceps mycelium, 60g of Zhulingcao, 80g of Ishimichuan, and 160g of Pennisetum as raw materials. The current extraction method is to add water and decoct twice, each time 2 -3 hours, combine the decoction, filter, concentrate into a thick paste, granulate, dry, press into 1000 tablets, coat with sugar, that is, it can improve immunity. [0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing Cordyceps mycelium. However, the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P35/00
Inventor 李洋
Owner 南京多宝生物科技有限公司
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