A chip-scale diamond nv ‑ Color center magnetic imaging device and imaging method

Abstract

The invention discloses a chip-level diamond NV-color center magnetic imaging device and method, and the method achieves the hyperfine magnetic field imaging of the two-dimensional surface of an object, such as a magnetic image of a biological cell. The method comprises the steps: carrying out the polarization of a laser pulse and a microwave pulse; generating fluorescent light generated at the NV-color center of a diamond in an external magnetic field; employing the laser pulse to generate fluorescent light again, wherein the difference result of fluorescent light of two times can reflect the magnetic field intensity of the NV-color center, thereby achieving the conversion of magnetic field information to optical information; and employing a nano-level convex lens group and a distributed optical imaging unit to convert an optical signal into an electric signal. The invention also relates to a packaging method for enabling a whole system to be packaged in a manner of chip level, and the method comprises temperature control and electromagnetic shielding. The method is great in value in the fields of biomedical research and medical diagnosis.

Description

technical field [0001] The present invention designs a chip-level diamond NV - The color center magnetic imaging device and method realize ultra-smart magnetic field imaging of two-dimensional surfaces, which can serve the magnetic image research of biological cells and medical image detection and other related fields. Background technique [0002] In the application process of existing bioimaging technology, due to insufficient detection resolution or detection sensitivity, it is not only difficult to meet the needs of research fields such as living tissue observation and cytopathological analysis, but even delays the early detection of various diseases including cancer. Discovery and treatment. In the existing field of micro-scale imaging, the imaging technologies that can be used for biological imaging can be divided into three types: optical imaging, photoelectric imaging and magnetic field measurement imaging. Among them, optical imaging has the disadvantages of requi...

AI Technical Summary

Problems solved by technology

In this context, due to the extremely high spatial resolution achieved by the diamond color center for magnetic field measurement, there is currently no better way to collect and measure it for ultra-high spatial resolution detection

At the same time, it is difficult to achieve miniaturization because it requires laser polarization, temperature and magnetic field environment control

[0003] Based on diamond NV - The magnetic field measurement of the color center has been recognized by the field of magnetic field measurement, and has achieved initial success. Currently, a single NV is mainly used - The color center is used as a magnetic field probe for magnetic field scanning imaging, but this method has a contradiction between spatial resolution and real-time measurement

At the same time, some researchers have proposed to directly detect high-concentration NV by CCD imaging. - Color center diamond for magnetic field measurement imaging, but this method only uses NV - The advantage of ultra-high magnetic field measurement sensitivity of color center diamond obliterates NV - The advantage of ultra-high spatial resolution of color center diamond reduces the spatial resolution to the size of the CCD imaging unit

Not only that, the research is also limited to the stage of laboratory platform, and has not yet achieved miniaturization in the field of application

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