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Application of a traditional Chinese medicine composition for soothing the liver and invigorating the spleen in the preparation of medicines for treating anxiety and depression

A technology for soothing the liver, strengthening the spleen, and anxiety and depression. It is used in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas. significant effect

Inactive Publication Date: 2018-09-18
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, apart from intervention methods such as exercise and psychology, there is no standardized clinical drug treatment to improve anxiety and depression in breast cancer patients

Method used

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  • Application of a traditional Chinese medicine composition for soothing the liver and invigorating the spleen in the preparation of medicines for treating anxiety and depression
  • Application of a traditional Chinese medicine composition for soothing the liver and invigorating the spleen in the preparation of medicines for treating anxiety and depression
  • Application of a traditional Chinese medicine composition for soothing the liver and invigorating the spleen in the preparation of medicines for treating anxiety and depression

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0022] Experimental Example 1: Clinical research on anxiety and depression in patients with breast cancer

[0023] 1.1 Test method: multi-center, randomized, double-blind, placebo-controlled clinical trial, with a total sample size of 118 cases, 59 cases in the treatment group and 59 cases in the control group. Grouping method: The study used the inter-group comparison between the treatment group and the control group; the before-and-after treatment and the self-control before and after treatment.

[0024] 1.2. Case selection

[0025] 1.2.1 Diagnosis and staging criteria: Refer to the NCCN Clinical Practice Guidelines for Breast Cancer.

[0026] 1.2.2 Inclusion criteria:

[0027] 2.1 Outpatient treatment of female breast cancer patients with clear pathological diagnosis

[0028] 2.2 Within 5 years after radical resection of breast cancer, radiotherapy or chemotherapy has been completed for more than 1 month

[0029] 2.3 No tumor recurrence or metastasis confirmed by clinic...

Embodiment 1

[0048] 1. Prescription:

[0049] Vinegar Bupleurum 100g, Poria 150g, Astragalus 300g, Angelica 100g, Paeoniae Alba 150g, Fried Atractylodes Rhizoma 150g, Albizia Julibrissin 150g, Ligustrum lucidum 150g, Polygala 120g, Rhodiola rosea 100g.

[0050] 2. Preparation method:

[0051] Add water to decoct all the herbs twice, the first time for 60 minutes, the second time for 30 minutes, filter, concentrate, dry, add appropriate amount of auxiliary materials, mix well, granulate, and pack into bags to obtain granules.

Embodiment 2

[0053] 1. Prescription:

[0054] Vinegar Bupleurum 90g, Poria 130g, Astragalus 230g, Angelica 90g, Paeoniae Alba 110g, Stir-fried Atractylodes Rhizoma 140g, Albizia Julibrissin 130g, Ligustrum lucidum 120g, Polygala 130g, Rhodiola rosea 90g.

[0055] 2. Preparation method:

[0056] Add water to decoct all medicinal flavors for 2 times, the first time for 60 minutes, the second time for 30 minutes, filter, concentrate, spray-dry, and pack separately to obtain.

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PUM

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Abstract

The invention discloses application of a traditional Chinese medicine composition soothing liver and strengthening spleen to preparation of a drug treating anxiety and depression of breast cancer patients. The traditional Chinese medicine composition is prepared from, by weight, 60-200 parts of vinegar processed radix bupleuri, 100-200 parts of poria cocos, 200-400 parts of astragali radix, 60-200 parts of angelica sinensis, 80-200 parts of white peony roots, 100-220 parts of fried rhizoma atractylodis, 100-180 parts of cortex albiziae, 100-180 parts of glossy privet fruit, 80-180 parts of polygala tenuifolia and 60-150 parts of rhodiola rosea. The clinical and trial study finds that the traditional Chinese medicine composition can be used for treating anxiety and depression of the breast cancer patients, and the effect is remarkable.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition for soothing the liver, in particular to an application of a pharmaceutical composition with the effect of soothing the liver and invigorating the spleen in preparing medicines for anxiety and depression of patients with breast cancer. Background technique [0002] Breast cancer is the most common type of malignant tumor in women, and 1 million people are newly diagnosed with breast cancer every year in the world. In recent years, the incidence of breast cancer in my country's urban and rural areas has shown an obvious upward trend. According to statistics, the incidence of female breast cancer in Beijing and Shanghai has reached 45 / 100,000 and 54.9 / 100,000 respectively, which have increased by 23% and 31% in ten years, which is close to the level of Western countries with high breast cancer incidence. Breast cancer has become the most threatening disease to women...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K36/69A61P25/24A61P25/22
Inventor 王笑民杨国旺郁仁存于明薇李琛
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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