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Pharmaceutical composition for treating myocardial infarction and preparing method thereof

A technology of myocardial infarction and composition, which is applied in the field of pharmaceutical composition for the treatment of myocardial infarction and its preparation, can solve the problem that the effect of nourishing qi and nourishing yin is not very significant, and achieve better drug treatment effect, less adverse reactions and good curative effect Effect

Inactive Publication Date: 2016-02-03
叶宗耀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent application 201410113088.8 discloses a pharmaceutical composition for the treatment of myocardial infarction. The raw materials for its preparation include: gallnut, honeysuckle, eucommia, thistle, chuanxiong, rehmannia glutinosa, cicada slough, poria cocos, white peony root, codonopsis and licorice. It has a good therapeutic effect in the treatment of myocardial infarction and has significant clinical promotion value, but the effect in nourishing qi and nourishing yin, promoting blood circulation and removing blood stasis is not very significant

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Five Zizi, 6 copies and 2 copies of Licorice.

[0033] The preparation method is as follows: Called Mu Jing, crushed into coarse powder, placed in the supercritical carbon dioxide extraction device, adds a volume score of 30%of the volume score of 30%of the rough powder, regulating the carbon dioxide flow of 20L / h, and the extraction pressure to 15MPa to 15MPaThe extraction temperature is 50 ° C and the extraction time is 2H. The decompression is separated to obtain the extract of the Jing Jing, retaining the residue of Mu Jing;Add the residual residue of Mu Jing, shatter, add 4 times the amount of water for 3 hours, boil for 60 minutes, filter, get the filter liquid, add 2 times the water to the filter, boil for 60 minutes, and then cook with the fire for 1 hour.Filter, get the filtrate, and combine the filtrate twice; mix the 牡 extract with the two filter fluids to the thick paste with a relative density of 1.25. The vacuum belt is dry at 60 ° C temperature.-0.09MPa, the ...

Embodiment 2

[0035] 10 Affiliated, 9 recreational grass and 10 licorice.

[0036]The preparation method is as follows: Called Mu Jing, crushed into coarse powder, placed in the supercritical carbon dioxide extraction device, adds a volume score of 45%of the volume score of 45%of the rough powder, regulates the carbon dioxide flow of 15L / h, and the extraction pressure is 18MPaThe extraction temperature is 45 ° C, and the extraction time is 2H. The decompression is separated to obtain the extract of Mu Jing, retaining the residue of Mu Jing;, Add the residue of the Mu Jing, shatter, add 5 times the amount of water for soaking for 2 hours, boil for 45 minutes, filter, get the filter liquid, add 4 times the water to the filter, boil for 30 minutes, then fry with the fire for 2 hours, and cook for 2 hours.Filter, get the filter fluid, and combine twice filter liquid; mix the peasted extract with the two filter fluids to the thick paste with a relative density of 1.35. The vacuum belt is dry at 60 °...

Embodiment 3

[0038] The drug composition of the present invention is prepared by the following weights: 15 copies, 15 copies of beef, 9 copies, 12 copies of dandelion, 15 copies of fennel, Cinnamon 12, 10 Affiliated, 9 Founds Cao and 10 Licorice.

[0039] The preparation method is similar to the embodiment 1.

[0040] Clinical efficacy observation

[0041] There is no statistical difference in the course of disease.

[0042] 2. Diagnostic criteria:

[0043] (1) Typical myocardial ischemic symptoms (chest pain or chest tightness discomfort);

[0044] (2) Typical ECG changes;

[0045] (3) Rising serum myocardial enzymes.

[0046] 3. Standards for evaluation of efficacy:

[0047] Treatment: After taking medicine, the symptoms of discomfort completely disappear;

[0048] Effective: After taking the drug, the symptoms of discomfort are reduced or partially disappeared;

[0049] Invalid: After taking the medicine, the symptoms of discomfort have not changed;

[0050] Total effectiveness = (cure+ef...

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating myocardial infarction and a preparing method thereof. The pharmaceutical composition is prepared from, by weight, 8-15 parts of vitex, 8-15 parts of pseudo-ginseng, 6-15 parts of burdock, 3-12 parts of dandelion, 6-15 parts of fennel, 9-12 parts of Chinese yam, 6-12 parts of dogwood, 6-12 parts of cinnamon, 3-12 parts of monkshood, 6-9 parts of red rhodobryum and 1-10 parts of liquorice. The pharmaceutical composition can invigorate blood circulation, remove stasis and tonify spleen and qi and has the advantages of being good in curative effect, mild in side effect, convenient to take, easy to apply and popularize and the like.

Description

Technical field [0001] The present invention is a Chinese medicine technology field, and especially involves a pharmaceutical composition and preparation methods that treat myocardial infarction. Background technique [0002] Myocardial infarction is part of the myocardial necrosis caused by myocardial lasting severe ischemia. Most of them occur in the middle age. The severe and lasting properties at the occurrence of the disease are similar to the symptoms of the front chest pain, palpitations, asthma, weak pulse, reduced blood pressure, and other symptoms.EssenceThe incidence of this disease has increased year by year. Arteriosclerosis accounts for 98%of the incidence of acute myocardial infarction. Patients are mostly 40 years old, and they are mostly accompanied by hypertension. Nearly half of the history of angina pectoris. [0003] In terms of treatment, it can be roughly divided into two categories: one is to treat the standard and the root cause, that isZhengzhi is a comm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P9/10
Inventor 叶宗耀
Owner 叶宗耀
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