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A kind of medicinal and edible composition with hypolipidemic function and preparation method thereof

A technology for a combination of medicine and food, applied in the field of health care products, can solve problems such as muscle lesions, unfavorable long-term use, etc., and achieve the effects of clear active ingredients, low toxic and side effects, and definite curative effect.

Active Publication Date: 2019-01-29
GUANGDONG ZHENGDANGNIAN BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the western medicines clinically used for lowering blood lipid mainly include fenofibrate, yadolate, furanmethrolone, statins, etc. The above-mentioned medicines all use statins as the main components. Although they can effectively reduce serum cholesterol levels, statins Similar drugs can cause muscle lesions, which is not conducive to long-term use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1, the preparation of natto extract

[0033] S1 After washing the soybeans, add water 3 times the weight of the soybeans and soak for 12 hours;

[0034] S2 Subpackage the soybeans obtained in step S1, sterilize them at 105°C for 30 minutes, add 1% of the above-mentioned Bacillus subtilis in the amount of soybeans when the product temperature is cooled to 30°C after sterilization, stir evenly, and then sterilize the soybeans at a temperature of 38°C. Cultivate for 40 hours at ℃ to get natto;

[0035] S3 Add sterile physiological saline to the natto obtained in step S2 under aseptic conditions at 25°C-30°C, the amount of physiological saline added is 1 times the weight of the natto, stir for 30 minutes, and filter to obtain an eluate;

[0036] S4 Mix the ascorbic acid solution with a concentration of 5% and the eluent obtained in step S3 at a volume ratio of 1:1, adjust the pH value to 7.0, pre-freeze at -8°C for 6 hours, and then put it in a temperature of -4...

Embodiment 2

[0037] Embodiment 2, the preparation of earthworm extract

[0038] S1 put the earthworms into a pressure-reducing container with a pressure of 92kPa and place it for 4 hours, then wash and drain;

[0039] S2, adding the above-mentioned earthworm weight 4 times the concentration of 1% sodium chloride solution to the earthworms obtained in step S1, then stirred in a homogenizer for 5 minutes, and left it for 4 hours to obtain a homogenate;

[0040] S3 Add the homogenate obtained in step S2 into a centrifuge with a rotating speed of 9800rpm and centrifuge for 10min, leave the supernatant, and pass the supernatant through an ultrafiltration membrane with a molecular weight cut-off of 8k, at a temperature of -60°C and a vacuum of 15pa Freeze for 3 hours, then dry at a temperature of 50°C for 12 hours.

Embodiment 3

[0042] prescription:

[0043] 10 parts of natto extract, 10 parts of earthworm extract, 8 parts of bamboo leaf flavonoids, 2 parts of hawthorn extract, 0.5 part of kudzu root extract, 0.1 part of ginseng extract, 0.1 part of green tea extract, 4 parts of chitosan oligosaccharide and 4 parts sorbitol.

[0044] Preparation:

[0045] S1 Mix natto extract, earthworm extract, hawthorn extract, kudzu root extract, ginseng extract and green tea extract evenly, and pass through a 18-mesh sieve to obtain a mixed fine powder;

[0046] S2 Add bamboo leaf flavonoids, chitosan oligosaccharide and sweetener to the mixed fine powder obtained in step S1, mix evenly, and add corresponding auxiliary materials to make capsules.

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PUM

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Abstract

The invention belongs to the field of health-care products and particularly relates to a dual-purpose medical and edible composition with a blood fat reducing function and a preparing method of the dual-purpose medical and edible composition. The dual-purpose medical and edible composition with the blood fat reducing function is mainly prepared from natto extract, earthworm extract, bamboo leaf flavonoid, hawthorn extract, pueraria extract, ginseng extract, green tea extract, chitosan oligosaccharide and a sweetening agent. The dual-purpose medical and edible composition with the blood fat reducing function can obviously reduce the TC and TG content of serum of hyperlipidemia rats, and can also obviously reduce the high shearing viscosity, medium shearing viscosity and low shearing viscosity of the blood of the hyperlipidemia rats, and thus it is indicated that the dual-purpose medical and edible composition with the blood fat reducing function has the obvious blood fat reducing effect. In addition, the composition is definite in effective ingredient, controllable in quality, low in toxic and side effect, high in safety and suitable for being taken in a long term and is ideal blood fat reducing health-care food.

Description

technical field [0001] The invention belongs to the field of health care products, and in particular relates to a medicinal and edible composition with the function of lowering blood fat and a preparation method thereof. Background technique [0002] Blood lipid is a general term for neutral fats (triglycerides and cholesterol) and lipids (phospholipids, glycolipids, sterols, steroids) in plasma, which are widely present in the human body. Blood lipid is an important substance in the human body and has many important functions, but it cannot exceed a certain range. Hyperlipidemia refers to high blood cholesterol (TC) and / or triglyceride (TG) or low high-density lipoprotein cholesterol (HDL-C). At present, patients with hyperlipidemia are extremely common. The hazards of hyperlipidemia are: if there is too much blood lipid, it is easy to cause "blood thickening", which deposits on the blood vessel wall and gradually forms small plaques. These "plaques" increase and increase...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00A61K36/899A61P3/06A61K35/62A61K31/7016A61K31/702A23L33/105
CPCA23V2002/00A61K9/1623A61K9/2018A61K9/4858A61K31/7016A61K31/702A61K35/62A61K36/258A61K36/48A61K36/488A61K36/734A61K36/82A61K36/899A61K2236/19A61K2236/333A61K2236/51A61K2300/00A23V2200/3262A23V2250/21
Inventor 江小元吴益芳
Owner GUANGDONG ZHENGDANGNIAN BIO TECH CO LTD
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