A biocidal plastic

A plastic and biological technology, applied in the field of plastics, can solve the problems of difficulty in finding, volatile and inactivation of biologically active molecules, etc., and achieve the effects of simple preparation method, harmless environmental pollution, and good bactericidal activity.

Active Publication Date: 2018-08-17
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, antibacterial plastics with natural bioactive molecules as active ingredients are rarely seen in the market at present. This is because the processing and molding of traditional thermoplastics is carried out at high temperatures (usually exceeding 100°C), which requires these antibacterial agents to be able to Resistant to high temperature without decomposing and denaturing, but because bioactive molecules are easily denatured and inactivated in high temperature environments, it is difficult to find a universal method to produce this antibacterial plastic

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Preparation of polystyrene and β-galactosidase composite plastics: 10 grams of polystyrene nanospheres with a particle size of 150 nm were prepared by emulsion polymerization, washed with absolute ethanol and distilled water for 5 times, and vacuum-dried for later use. Dissolve 10 mg of β-galactosidase in 10 ml of sterile distilled water, stir well, and dissolve to a homogeneous system. Add 10 grams of polystyrene pellets into the system, stir quickly to form a uniform suspension, drain the suspension, put it into a mold and spread it flat, put it into a press through the mold, and heat it at 40°C Apply a pressure of 250 MPa under the same conditions, and keep the pressure for 20 minutes, release the pressure, and demould, and the composite plastic of polystyrene and β-galactosidase can be obtained.

Embodiment 2

[0018] Design comparative experiments, respectively adopt the traditional thermoplastic processing method and the preparation method at room temperature of the present invention to prepare polystyrene and β-galactosidase composite materials, and use β-galactosidase to catalyze the hydrolysis of β-D Galactopyranoside (RBG) to generate red fluorescent product properties, in verifying whether the activity of the enzyme is maintained, the test results are as follows figure 1 , where the ordinate is the fluorescence intensity of the enzyme-catalyzed reaction product, and the abscissa is the reaction time.

[0019] Depend on figure 1 It can be seen that when the composite material prepared by the traditional thermoplastic processing method catalyzes the hydrolysis of β-D galactopyranoside (RBG), due to the disappearance of the enzyme activity, the reaction cannot proceed, so its fluorescence intensity has been kept at a low level. The numerical value of β-galactosidase remains unch...

Embodiment 3

[0021] Preparation of polyvinyl chloride and bovine serum albumin (BSA) composite plastics: 5 grams of polyvinyl chloride nanospheres with a particle size of about 40 nm were prepared by nanoparticle sedimentation method, washed with absolute ethanol and distilled water for 5 times respectively, and vacuum Dry and set aside. Dissolve 1 gram of bovine serum albumin in 10 ml of sterile distilled water, fully stir and dissolve to a uniform system, add 5 grams of polyvinyl chloride nanospheres to the system, stir rapidly to form a uniform suspension, and mix the After the suspension is drained, put it into a mold and pave it flat, put it into a press through the mold, apply a pressure of 100MPa at 0°C, and keep the pressure for 1min, then release the pressure and demould to obtain polyvinyl chloride and Composite plastic of bovine serum albumin.

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Abstract

The invention discloses a biological bactericidal plastic. A preparation method of the biological bactericidal plastic includes the following steps that biologically-active antibacterial molecules are dissolved in water to be prepared into a mixed solution system, polymer nano-particles are added in the system and evenly mixed, then the mixture is subjected to swab-off and placed in a mould to be pressed at room temperature, and the biological bactericidal plastic is obtained. The biological bactericidal plastic has the advantages that the polymer nano-particles serve as a carrier, the natural biologically-active antibacterial molecules are compounded at the room temperature (0-40 DEG C), and then the biological bactericidal plastic is obtained; the plastic is good in bactericidal activity and slow release property and not likely to cause environmental pollution, and does no harm to human health; meanwhile, the preparation method of the biological bactericidal plastic is simple, environmentally friendly and capable of being widely applied to various biological antibacterial molecule systems and various macromolecule systems.

Description

technical field [0001] The invention belongs to the field of plastics, in particular to a biological sterilization plastic. Background technique [0002] Antibacterial plastic is a special plastic with antibacterial or bactericidal properties. It is usually obtained by blending a plastic masterbatch with a certain amount of antibacterial agent and granulating it. Various industrial products can be produced through injection molding or blow molding. At present, the bacteriostatic agents commonly used in antibacterial plastics are mainly divided into two categories, one is inorganic antibacterial agents, and the other is organic antibacterial agents. However, these chemical antibacterial agents often easily cause environmental pollution or have certain hazards to human health. [0003] Natural biological antibacterial agents have the advantages of high efficiency, harmlessness and environmental friendliness. With the enhancement of people's awareness of environmental protecti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L25/06C08L27/06C08L89/00C08L5/08
CPCC08L25/06C08L27/06C08L89/00C08L5/08
Inventor 薛奇李翔王晓亮周东山徐洁滕超李林玲
Owner NANJING UNIV
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