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Fractional Flow Reserve (ffr) Indicator Using Adaptive Boundary Condition Parameters

A technique of fractional blood flow reserve and boundary conditions, applied in blood flow measurement, instruments for radiological diagnosis, applications, etc., can solve problems such as affecting FFR, resistance is not constant, estimation error, etc.

Active Publication Date: 2019-03-12
KONINKLJIJKE PHILIPS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, in reality, this resistance is not constant, and it affects the FFR
Therefore, this method may cause estimation error

Method used

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  • Fractional Flow Reserve (ffr) Indicator Using Adaptive Boundary Condition Parameters
  • Fractional Flow Reserve (ffr) Indicator Using Adaptive Boundary Condition Parameters
  • Fractional Flow Reserve (ffr) Indicator Using Adaptive Boundary Condition Parameters

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Embodiment Construction

[0014] An iterative method for determining the FFR metric is described below. The method involves first assuming that all vessels are healthy, and using CFD simulation with resistance boundary condition estimation to determine the FFR index. Next, the resistance boundary condition is iteratively corrected according to the severity of stenosis estimated by the FFR index from the previous iteration. Subsequent FFR metrics are then determined based on the corrected boundary conditions. The iterative process of correcting the resistance boundary conditions and computing another FFR metric continues until the stopping criterion is satisfied. Then output the final FFR index.

[0015] figure 1 An imaging system 100 such as a CT scanner is schematically illustrated. Imaging system 100 includes a generally fixed gantry 102 and a rotating gantry 104 rotatably supported by fixed gantry 102 and rotating about an examination region 106 about a z-axis. A subject support 108 , such as a...

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Abstract

One method includes obtaining boundary condition estimates. The boundary condition estimate includes at least an estimated outlet resistance of the vessel with stenosis. The method also includes correcting the boundary condition estimate based on the severity of the stenosis, thereby creating a corrected boundary condition. The method also includes determining an FFR index based on the corrected boundary conditions. The method also includes displaying the FFR indicator. A computing system (122) includes a computer-readable storage medium (126) having instructions (124) for at least iteratively determining an FFR indicator based on a severity of narrowing of a blood vessel. The computing system also includes a computer processor (120) that processes the instructions and generates the FFR index based on the severity of the narrowing of the blood vessel.

Description

technical field [0001] The following relates generally to fractional flow reserve (FFR) metrics and more specifically to the use of adaptive boundary conditions to determine FFR metrics, and is described with a specific application to computed tomography (CT). However, the following also applies to other imaging modalities, including X-ray, Magnetic Resonance Imaging (MRI), and / or other imaging modalities. Background technique [0002] The FFR index is an indicator of the functional severity of coronary stenosis, which is calculated from pressure measurements taken during coronary angiography and is defined as the distal relative to the proximal (near the orifice) pressure under hyperemic conditions (narrow back) blood pressure. That is, the FFR index expresses the maximum flow along a blood vessel in the presence of a stenosis as compared to the maximum flow assuming no stenosis. FFR values ​​are absolute numbers between 0 and 1, where a value of 0.50 indicates that a giv...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/02A61B6/00G16H50/20
CPCA61B6/5217A61B5/02007A61B6/032A61B5/026A61B5/055G16H50/50A61B6/504G16H50/30A61B6/03
Inventor G·吉勒博阿Y·拉马什L·戈申
Owner KONINKLJIJKE PHILIPS NV