Colloidal bismuth pectin capsule containing galangal extract and preparation method of colloidal bismuth pectin capsule

A technology of galangal extract and colloidal bismuth pectin, applied in the field of colloidal bismuth pectin capsule containing galangal extract and its preparation, can solve the problems of serious drug side effects and single treatment mechanism, and achieve strong antibacterial effect, Raw material formula is reasonable, and the effect of enhancing the immune adhesion function of human macrophages

Inactive Publication Date: 2016-08-10
ZHENGZHOU SIBIAN TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of this, the purpose of the present invention is to address the deficiencies in the prior art, to provide a colloidal bismuth pectin capsule containing galangal extract and a preparatio

Method used

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  • Colloidal bismuth pectin capsule containing galangal extract and preparation method of colloidal bismuth pectin capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A colloidal bismuth pectin capsule containing galangal extract, comprising the following raw materials in parts by weight: 30 parts of colloidal bismuth pectin (calculated as bismuth), 10 parts of galangal extract, 80 parts of starch, 7 parts of sodium carboxymethyl starch, 4 parts of talcum powder, 2 parts of low-substituted hydroxypropyl cellulose, 0.2 parts of magnesium stearate and 4 parts of gastric-soluble Opadry powder.

[0031] Its preparation method comprises the following steps:

[0032] (1) Raw material pretreatment: respectively pulverize colloidal bismuth pectin, galangal extract, filler, disintegrant, glidant, binder, and lubricant and pass through a 250-mesh sieve, then mix evenly to obtain a mixed powder ;

[0033] (2) Preparation of pellets: the mixed powder obtained in step (1) is prepared by rolling and agglomerating into a circle to obtain pellets;

[0034] (3) Prepare coating spray solution: dissolve 4 parts of gastric-soluble Opadry powder in 200...

Embodiment 2

[0040] A colloidal bismuth pectin capsule containing galangal extract, comprising the following raw materials in parts by weight: 50 parts of colloidal bismuth pectin calculated as bismuth, 4 parts of galangal extract, 160 parts of sucrose, and croscarmellose sodium 11 parts, 2 parts of talcum powder, 6 parts of polyethylene glycol, 2.8 parts of palmitic alcohol and 8 parts of gastric soluble Opadry powder.

[0041] Its preparation method comprises the following steps:

[0042] (1) Raw material pretreatment: respectively pulverize colloidal bismuth pectin, galangal extract, filler, disintegrant, glidant, binder, and lubricant, pass through a 300-mesh sieve, and then mix evenly to obtain a mixed powder ;

[0043] (2) Preparation of pellets: the mixed powder obtained in step (1) is prepared by rolling and agglomerating into a circle to obtain pellets;

[0044] (3) Preparation of coating spray liquid: Dissolve 8 parts of gastric-soluble Opadry powder in 400 parts of 90wt% ethan...

Embodiment 3

[0050] A colloidal bismuth pectin capsule containing galangal extract, comprising the following raw materials in parts by weight: 35 parts of colloidal bismuth pectin (calculated as bismuth), 6 parts of galangal extract, 150 parts of lactose, 8 parts of cross-linked polyvinylpyrrolidone, 3 parts of talcum powder, 3 parts of methylcellulose, 0.6 parts of magnesium stearate and 5 parts of gastric soluble Opadry powder.

[0051] Its preparation method comprises the following steps:

[0052] (1) Raw material pretreatment: respectively pulverize colloidal bismuth pectin, galangal extract, filler, disintegrant, glidant, binder, and lubricant and pass through a 270-mesh sieve, then mix evenly to obtain a mixed powder ;

[0053] (2) Preparation of pellets: the mixed powder obtained in step (1) is prepared by rolling and agglomerating into a circle to obtain pellets;

[0054] (3) Preparation of coating spray liquid: Dissolve 5 parts of gastric soluble Opadry powder in 250 parts of 90...

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Abstract

The invention discloses a colloidal bismuth pectin capsule containing a galangal extract and a preparation method of the colloidal bismuth pectin capsule. The colloidal bismuth pectin capsule containing the galangal extract is prepared from the following raw materials in parts by weight: 30 to 50 parts of colloidal bismuth pectin according to bismuth, 4 to 10 parts of the galangal extract, 80 to 160 parts of a filler, 7 to 11 parts of a disintegrating agent, 2 to 4 parts of talcum powder, 2 to 6 parts of an adhesive, 0.2 to 2.8 parts of a lubricating agent and 4 to 8 parts of gastric solubility opadry powder. The raw materials of the colloidal bismuth pectin capsule are reasonable in formula, and the prepared colloidal bismuth pectin capsule has a uniform and complete appearance; from protection of gastric mucosa, improvement of the immunity of a human body and improvement of the antibacterial ability of the human body, effects of quickly relieving gastric ulcer diseases and fundamentally curing gastric ulcer.

Description

technical field [0001] The invention relates to a bismuth agent and a preparation method thereof, in particular to a colloidal pectin bismuth capsule containing galangal extract and a preparation method thereof. Background technique [0002] At present, there are several clinical treatment options for gastritis and gastric ulcer as follows: (1) antacid therapy, which aims to neutralize gastric acid, such as aluminum hydroxide; (2) gastric acid secretion inhibitor, which plays a role in inhibiting gastric acid secretion Strong inhibitory effect, such as cimetidine and famotidine; (3) Gastric mucosa protective agents, for the purpose of protecting the damaged gastric mucosa and accelerating the healing of gastric mucosal ulcers, such as sucralfate and various bismuth agents (4) Improving human immunity and antibacterial effect, such as various Chinese herbal medicine compositions used to treat gastric ulcer. [0003] Colloidal bismuth pectin is a colloidal bismuth preparation...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61K31/732A61K9/52A61P1/04A61P31/04
CPCA61K36/9062A61K9/5042A61K9/5084A61K33/245A61K2300/00
Inventor 闵玉涛
Owner ZHENGZHOU SIBIAN TECH CO LTD
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