Fermentation grape extract, preparing method of fermentation grape extract and preparation containing fermentation grape extract

A technology for extracts and grapes, which is applied in the field of fermented grape extracts and its preparation and preparations containing them, can solve the problems of no relevant patents on grape polyphenols, and achieve the effects of novel technology, improved extraction rate, and enhanced antioxidant enzyme activity

Inactive Publication Date: 2016-08-31
UBASIC TIANJIN BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no relevant patents and literatures on the method of fermenting whole grapes and extracting grape polyphenols from the fermented liquid and filter residue.

Method used

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  • Fermentation grape extract, preparing method of fermentation grape extract and preparation containing fermentation grape extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Example 1 Fermented Grape Extract

[0052] The preparation method comprises the following steps:

[0053] 1) Wash and crush whole grape raw materials (including grape vines, grape leaves, grape stems, grape skins, grape seeds, etc.)

[0054] 2) filtering the fermented liquid to obtain filtrate A;

[0055] 3) drying and pulverizing the filtered filter residue, adding 80% ethanol which is 8 times the dry weight of the filter residue, extracting at room temperature for 4 hours, and filtering to obtain an extract;

[0056]4) combining the filtrate A and the extract, concentrating to dryness, and obtaining the crude extract of fermented grapes;

[0057] 5) dissolving the obtained crude extract in a mixture of ethanol and ethyl acetate with a volume ratio of 2:3, filtering, discarding the filter residue, and obtaining filtrate B;

[0058] Pass the filtrate B through the macroporous adsorption resin column D-101, elute with a mixture of ethanol and ethyl acetate with a volu...

Embodiment 2

[0061] Example 2 Fermented Grape Extract

[0062] The preparation method comprises the following steps:

[0063] 1) Wash and crush whole grape raw materials (including grape vines, grape leaves, grape stems, grape skins, grape seeds, etc.)

[0064] 2) filtering the fermented liquid to obtain filtrate A;

[0065] 3) drying and pulverizing the filtered filter residue, adding 70% ethanol which is 8 times the dry weight of the filter residue, extracting at room temperature for 4 hours, and filtering to obtain an extract;

[0066] 4) combining the filtrate A and the extract, concentrating to dryness, and obtaining the crude extract of fermented grapes;

[0067] 5) dissolving the obtained crude extract in a mixture of ethanol and ethyl acetate with a volume ratio of 2:3, filtering, discarding the filter residue, and obtaining filtrate B;

[0068] Pass the filtrate B through the macroporous adsorption resin column D-101, elute with a mixture of ethanol and ethyl acetate with a vol...

Embodiment 3

[0071] Example 3 Tablet containing the fermented grape extract of Example 1

[0072] Composition of raw and auxiliary materials: Example 1 fermented grape extract 25kg, starch 4.8kg, magnesium stearate 125g.

[0073] Preparation method: take the fermented grape extract of Example 1, grind it into fine powder, pass through a 100-mesh sieve, use 50% starch slurry as a binder, granulate and dry in a one-step granulator, add magnesium stearate, Mix well, compress into tablets, and coat with sugar.

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PUM

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Abstract

The invention relates to a fermentation grape extract, a preparing method of the fermentation grape extract and a preparation containing the fermentation grape extract. The fermentation grape extract contains grape polyphenol and resveratrol. A method for fermenting full grapes with saccharomycetes is utilized, polyphenol substances in full grapes are extracted, and the extraction rate is obviously increased. Meanwhile, operation is simple, cost is low, and the fermentation grape extract is suitable for industrial production. Experiments verify that the fermentation grape extract can remarkably improve the activity of antioxidase in rice and has the anti-oxidation function and an effect better than that achieved in the prior art.

Description

technical field [0001] The invention relates to a fermented grape extract, a preparation method thereof and a preparation containing the same, in particular to a method for preparing grape extract by fermenting whole grapes. Background technique [0002] Grape polyphenols have strong antioxidant activity, have significant effects in anti-inflammation, anti-mutation, anti-tumor and anti-cardiovascular and cerebrovascular diseases, and can effectively protect normal cells from damage. The resveratrol contained in it has received widespread attention in recent years. Resveratrol is a chemical substance produced by organisms to resist environmental stress (such as bad weather, microbial infection, etc.), and has significant pharmacological and biological effects, such as anti-cancer, nerve protection, anti-aging, anti-inflammation, and life extension Wait. [0003] Grapes are one of the most productive fruits in the world. Grape vines, grape leaves, grape stems, grape skins an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A61K36/87A61P39/06
CPCA61K36/87A23V2002/00A61K31/05A61K2236/19A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 李赫宇王磊张东星李晴
Owner UBASIC TIANJIN BIOTECH CO LTD
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