Oral local anesthetic preparation and preparation method thereof

A technology of local anesthesia and preparation, which is applied in the field of local anesthesia on the body surface, can solve problems such as cumbersome operation and difficulty in speaking, achieve the effects of reducing the injection dose, increasing the effect of analgesia, calming the nerves and stopping bleeding, and avoiding muscle pain

Inactive Publication Date: 2016-08-31
雷知雅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing anesthesia methods are relatively cumbersome to operate, and there are also risks of anesthesia. Minor complications that may occur include muscle pain, teeth, dentures, lip and tongue injuries, temporary difficulty breathing, difficulty speaking, and nerve damage. Serious complications Such as heart attack, stroke, severe allergic reaction, brain / lung damage, kidney / liver failure, permanent nerve damage, eye injury, throat damage, and pneumonia, although the chances of these complications are minimal , but it is necessary to prevent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] An oral local anesthetic preparation prepared by weight ratio of the following raw materials: procaine hydrochloride 0.5%, metronidazole 0.001%, disodium edetate 0.0005%, traditional Chinese medicine extract 5% and 0.9% The remaining amount of sodium chloride and physiological saline; the traditional Chinese medicine extract is prepared according to its own weight parts of the following raw materials: 10 parts of anti-sunflower extract, 5 parts of Yunshi extract, 5 parts of Zanthoxylum bungeanum extract, Huashan 3 parts of ginseng extract, 3 parts of old crane grass extract, 10 parts of skullcap extract, 3 parts of coptis extract, 3 parts of dandelion extract, and 5 parts of Ligusticum chuanxiong extract.

[0016] The preparation method of the oral local anesthetic preparation includes the following steps:

[0017] ⑴ Preparation of Chinese medicine extract

[0018] ① After drying, pulverize and pass a 100-mesh sieve. Add 4 times the weight of water to the resulting powder and...

Embodiment 2

[0022] An oral local anesthetic preparation prepared by weight ratio of the following raw materials: procaine hydrochloride 1.5%, metronidazole 0.002%, disodium ethylenediaminetetraacetic acid 0.0015%, traditional Chinese medicine extract 7% and 0.9% The remaining amount of sodium chloride and physiological saline; the traditional Chinese medicine extract is prepared according to its own weight parts of the following raw materials: 15 parts of anti-sunflower extract, 10 parts of Yunshi extract, 10 parts of Zanthoxylum bungeanum extract, Huashan 7 parts of ginseng extract, 7 parts of geranium extract, 15 parts of skullcap extract, 7 parts of coptis extract, 7 parts of dandelion extract, and 10 parts of Ligusticum chuanxiong extract.

[0023] The preparation method of the oral local anesthetic preparation includes the following steps:

[0024] ⑴ Preparation of Chinese medicine extract

[0025] ① After drying, pulverize and pass through a 120-mesh sieve. Add 6 times the weight of water...

Embodiment 3

[0029] An oral local anesthetic preparation prepared by weight ratio of the following raw materials: procaine hydrochloride 1%, metronidazole 0.0015%, disodium edetate 0.001%, traditional Chinese medicine extract 6% and 0.9% The remaining amount of sodium chloride and physiological saline; the traditional Chinese medicine extract is prepared according to its own weight parts of the following raw materials: 12 parts of anti-sunflower extract, 8 parts of Yunshi extract, 7 parts of Zanthoxylum bungeanum extract, Huashan 5 parts of ginseng extract, 5 parts of old crane grass extract, 12 parts of skullcap extract, 5 parts of coptis extract, 5 parts of dandelion extract, and 8 parts of Ligusticum chuanxiong extract.

[0030] The preparation method of the oral local anesthetic preparation includes the following steps:

[0031] ⑴ Preparation of Chinese medicine extract

[0032] ① After drying, pulverize and pass through a 120-mesh sieve. Add 5 times the weight of water to the resulting powd...

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PUM

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Abstract

The invention discloses an oral local anesthetic preparation and a preparation method thereof and belongs to the field of surface local anesthesia medicine. The preparation is prepared from procaine hydrochloride, metronidazole, ethylene diamine tetraacetic acid, traditional Chinese medicine extracts and 0.9% sodium chloride normal saline. The traditional Chinese medicine extracts are prepared from oreoselinum extracts, mysorethorn extracts, wild pepper extracts, physochlaina infundibularis extracts, Erodium stephanianum Willd extracts, radix scutellariae extracts, coptidis rhizoma extracts, dandelion extracts and rhizoma chuanxiong extracts. Procaine hydrochloride is combined with traditional Chinese medicine extract components such as oreoselinum, mysorethorn and wild pepper, so that a series of adverse reactions such as muscular pain, tooth pain and heart attack caused when conventional procaine hydrochloride injections are applied to oral anesthesia are avoided, the anesthetic effect is improved, and anesthetic time is prolonged; dosage of procaine hydrochloride injection is reduced, the effects of stopping pain, calming the nerves and stopping bleeding are improved, and safety is improved.

Description

Technical field [0001] The invention belongs to the field of local anesthetics for body surface, and specifically relates to an anesthetic preparation for oral anesthesia and a preparation method thereof. Background technique [0002] In clinical surgery, anesthesia is a variety of methods used to eliminate pain, ensure patient safety, and create good surgical conditions during surgery or diagnostic examination operations. The patient feels pain during surgery or diagnostic examination and requires anesthetics or other means to temporarily lose consciousness. Surgery or inspection operations can also cause mental stress and reflex adverse reactions, such as gastrointestinal surgery can cause nausea and vomiting. Long-term uncomfortable posture can increase the discomfort and pain of the patient. Therefore, the patient should be operated in a comfortable and quiet environment without responding to adverse stimuli and temporarily losing memory. [0003] Oral anesthetics are one of ...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61K9/08A61P23/02A61K31/245
CPCA61K31/245A61K9/0019A61K9/08A61K36/185A61K36/23A61K36/236A61K36/288A61K36/48A61K36/539A61K36/718A61K36/758A61K36/81A61K47/183A61K47/22A61K2236/331A61K2236/39A61K2300/00
Inventor 雷知雅
Owner 雷知雅
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