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Bitter aversive agent and preparation method thereof

An aversive and bitterness technology, applied in the field of bitterness aversive and its preparation, can solve the problems of children's damage, can only be painted on the nails, and the oil agent has no foothold, and achieves the promotion of nail bed growth, convenient application, and promotion of hand skin repair. Effect

Inactive Publication Date: 2016-10-12
周国文
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The advantage of water agent is that it can be applied in a wide range, and you can apply it wherever you want; the disadvantage is that it is not easy to dry after application, and the bitterness is easily worn off or washed off by water. It is very troublesome to apply it every hour
Another disadvantage of water preparations is that they are easy to deteriorate. Manufacturers have to add high-concentration preservatives to prolong the shelf life, which is harmful to children's lips, digestive tract, and hand skin.
The advantage of the oil is that it is easy to dry, and the bitter taste is not easy to wear off; but the disadvantage is that it can only be applied to the nails, not the skin of the hands. Some children have bitten off their nails, and the oil has no foothold.
In addition, the oil contains benzene, acetone, formaldehyde and other harmful substances, which will cause damage to the child's nail bed and the whole body.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 of the present invention provides a kind of bitter taste aversion agent, and this aversion agent comprises the raw material of following weight portion:

[0032] 490-510 parts of bitter substances carrier, 0.042-0.046 parts of bitter substances and 4.5-5.5 parts of additives;

[0033] Wherein, the bitter substance carrier is aloe stock solution, the bitter substance is a saturated solution of denatonium benzoate and water in a ratio of 1:1000, and the additives include sodium hydroxide solution, chondroitin, carbomer and chamomile hydrosol. In practical application, the additive includes 1.4-1.6 parts of chondroitin. The saturated solution of denatonium benzoate selected by the application and water according to the ratio of 1: 1000 is the most bitter substance in the world known at present, and the required bitterness intensity can be achieved with a very small amount; and in long-term medical practice, it is found that The saturated solution mixed with ...

Embodiment 2

[0035] Embodiment 1 of the present invention provides a kind of bitter taste aversion agent, and this aversion agent comprises the raw material of following weight part:

[0036] 490 grams of bitter substances carrier, 0.042 grams of bitter substances and 4.5 grams of additives;

[0037] Wherein, the carrier of the bitter substance is aloe stock solution, the bitter substance is a saturated solution of denatonium benzoate and water according to this example of 1:1000, and the additives include sodium hydroxide solution, chondroitin, carbopol Hummus and Chamomile Hydrosol. In practical application, 1.4 grams of chondroitin are included in the additive.

Embodiment 3

[0039] Embodiment 1 of the present invention provides a kind of bitter taste aversion agent, and this aversion agent comprises the raw material of following weight part:

[0040] 500 grams of bitter substances carrier, 0.045 grams of bitter substances and 5 grams of additives;

[0041] Wherein, the bitter substance carrier is aloe stock solution, the bitter substance is a saturated solution of denatonium benzoate and water in a ratio of 1:1000, and the additives include sodium hydroxide solution, chondroitin, carbomer and chamomile hydrosol. In practical application, 1.5 grams of chondroitin are included in the additive.

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PUM

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Abstract

The invention discloses a bitter aversive agent and a preparation method thereof. The aversive agent can consist of a bitter substance carrier, a bitter substance and additives. According to the bitter aversive agent and the preparation method thereof provided by the invention, a fresh aloe original fluid is taken as the bitter substance carrier and is matched with a small quantity of chondroitin, and the bitter substance, assisted by two materials, namely the aloe and the chondroitin, can easily permeate into fingernails and subcutaneous tissues; and after 5min of washing a hand coated with the bitter aversive agent, bitterness is still quite strong. The aversive agent is convenient to coat; the aversive agent is applicable to both the fingernails and skin, and the aversive agent is washing-resistant, wear-resistant, free from preservatives and free from toxic and harmful materials; such allergic substances as calcium oxalate, rheum emodin and the like in aloe leaves are effectively eliminated in a process of preparing the bitter substance carrier, so that the bitter aversive agent is quite suitable for young people and children. The aloe ingredient and the chondroitin are also conducive to the repair of collagen tissues in nail beds and the skin, so as to promote the growth of the nail beds and the repair of the hand skin.

Description

technical field [0001] The invention relates to the technical field of aversion agents, in particular to a bitter aversion agent for assisting in correcting bad habits such as nail biting and a preparation method thereof. Background technique [0002] About 8% of children and adolescents have bad behaviors such as biting nails, gnawing hands, and eating fingers. This is a kind of acquired psychological behavior disorder, and once addicted, it is very stubborn. The currently recognized correction method is to apply a bitter aversive agent on the bitten part, so that the patient will feel disgusted with the nail after biting the bitter taste, and form a new conditioned reflex mechanism to achieve the purpose of correcting bad behavior habits. Currently, there are related treatment products available on the market, such as Daum-exol from Germany, URGO-STOP from France, and MAMALA-STOP from Britain. Although there are many types of such products, there are no more than two dosa...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/886A61K31/167A61K47/46A61K47/36A61P17/02A61P25/00A61K31/737
CPCA61K36/896A61K9/0014A61K31/167A61K31/737A61K36/287A61K36/886A61K47/36A61K47/46A61K2300/00
Inventor 周国文
Owner 周国文
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