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Pharmaceutical composition for preventing and treating bladder cancer

A composition and technology for bladder cancer, applied in drug combinations, antineoplastic drugs, pharmaceutical formulations, etc., can solve the problems of adverse reactions of chemotherapy drugs, many adverse reactions, and failure to be widely used

Inactive Publication Date: 2016-10-26
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The failure of chemotherapy drugs, the adverse reactions of patients to chemotherapy drugs and the influence of chemotherapy drugs on normal cells are the reasons that restrict the development of its clinical application.
Immunosuppressants such as interleukin-2 and interferon have not been widely used due to many adverse reactions, ineffective for some patients, and price factors.

Method used

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  • Pharmaceutical composition for preventing and treating bladder cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: The pharmaceutical composition of preventing and treating bladder cancer and its preparation method

[0038] The composition and parts by weight of the raw materials of the pharmaceutical composition for preventing and treating bladder cancer are: 805g of goose egg shell, 754g of blue tang fruit, 745g of zebra lipped wormwood, 68g of agrimones, 35g of pseudohypericum bisanthraquinone, and 22g of violaline;

[0039] Preparation:

[0040] (1) According to the proportion of raw materials, take blue tang fruit, zebra lip sage, goose egg shell, agrimony lactone, pseudohypericum bisanthraquinone, and cordyline alcohol, mix well, and use 33% ethanol by weight As a solvent, extract by warm dipping at 20.5°C, the number of extractions is 27 times, each extraction time is 16 hours, and the amount of solvent used each time is 23 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extracted Solution A recovers ethano...

Embodiment 2

[0043] Embodiment 2: the pharmaceutical composition of preventing and treating bladder cancer and preparation method thereof

[0044] The composition and parts by weight of the raw material drug of the pharmaceutical composition for preventing and treating bladder cancer are: 800g of goose egg shell, 758g of blue tang fruit, 740g of zebra lipped wormwood, 70g of agrimony lactone, 30g of pseudohypericum bisanthraquinone, and 24g of violaline;

[0045] Preparation:

[0046] (1) According to the proportion of raw materials, take blue tang fruit, zebra lip sage, goose egg shell, agrimony lactone, pseudohypericum bisanthraquinone, and cordyline alcohol, mix well, and use 33% ethanol by weight As a solvent, extract by warm dipping at 20.5°C, the number of extractions is 27 times, each extraction time is 16 hours, and the amount of solvent used each time is 23 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extracted Solution A ...

Embodiment 3

[0049] Embodiment 3: the pharmaceutical composition of preventing and treating bladder cancer and preparation method thereof

[0050] The composition and parts by weight of the raw material drug of the pharmaceutical composition for preventing and treating bladder cancer are: 810g of goose egg shell, 750g of blue pineapple, 750g of zebra lipped wormwood, 65g of agrimony lactone, 40g of pseudohypericum bisanthraquinone, and 20g of violaline;

[0051] Preparation:

[0052] (1) According to the proportion of raw materials, take blue tang fruit, zebra lip sage, goose egg shell, agrimony lactone, pseudohypericum bisanthraquinone, and cordyline alcohol, mix well, and use 33% ethanol by weight As a solvent, extract by warm dipping at 20.5°C, the number of extractions is 27 times, each extraction time is 16 hours, and the amount of solvent used each time is 23 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extracted Solution A r...

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Abstract

The invention discloses a pharmaceutical composition for preventing and treating bladder cancer and a preparation method thereof. The pharmaceutical composition of the invention is composed of goose egg shell, blue tang fruit, zebra lip sage, Agrimony lactone, pseudohypericum bisanthraquinone, Corydalis alkaloid is a raw material medicine, which is prepared in proportion, and can be made into various dosage forms according to conventional preparation technology, and has remarkable curative effect in preventing and treating bladder cancer.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating bladder cancer and a preparation method thereof. Background technique [0002] Bladder cancer is the most common malignant tumor in the genitourinary system, and its incidence rate ranks fourth among male tumors and ninth among female tumors. Non-muscle-invasive bladder cancer accounts for about 75%-85%, and the prognosis is good, but there is still a 70% recurrence rate, and 1%-45% can progress to muscle-invasive bladder cancer within a few years. Urethral bladder tumor resection, postoperative intravesical infusion of chemotherapy drugs and immunosuppressants, etc. to prevent recurrence, delay progression and eliminate residual tumors and carcinoma in situ. The failure of chemotherapy drugs, the adverse reactions of patients to chemotherapy drugs and the influence of chemotherapy drugs o...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61P35/00A61P13/10A61K35/57A61K36/35A61K31/122A61K31/366A61K31/4355
CPCA61K35/57A61K31/122A61K31/366A61K31/4355A61K36/35A61K36/80A61K2236/333A61K2236/39A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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