Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Autofluorescence detection and imaging of bladder cancer realized through a cystoscope

a cystoscope and autofluorescence technology, applied in the direction of fluorescence/phosphorescence, spectroscopy, instruments, etc., can solve the problems of short photon penetration depth in tissues, time-consuming and bulky diagnostic equipment, and extraction of information, etc., to achieve cost-effective effects

Inactive Publication Date: 2008-02-28
LAWRENCE LIVERMORE NAT SECURITY LLC
View PDF11 Cites 25 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention provides a diagnostic apparatus and method for characterizing tissue components using electromagnetic radiation sources and near-infrared scattered and / or autofluorescence emission radiation. The apparatus includes an interior examination device, a detector, and a computer with image processing software. The method involves interrogating tissue components with the apparatus, detecting scattered and / or autofluorescence radiation, and characterizing the detected radiation. The invention provides a portable, cost-effective, non-invasive arrangement for tissue imaging that can differentiate components in human and animal tissues.

Problems solved by technology

Diagnostic medical equipment typically includes time-consuming, bulky, expensive apparatus that often exposes human tissue components to potentially harmful radiation and or chemicals.
The disadvantage of these wavelengths is their short photon penetration depth in tissues, which leads to extraction of information only from superficial tissue layers.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Autofluorescence detection and imaging of bladder cancer realized through a cystoscope
  • Autofluorescence detection and imaging of bladder cancer realized through a cystoscope
  • Autofluorescence detection and imaging of bladder cancer realized through a cystoscope

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] Referring now to the drawings, specific embodiments of the invention are shown. The detailed description of the specific embodiments, together with the general description of the invention, serves to explain the principles of the invention.

[0023] Unless otherwise indicated, all numbers expressing quantities of ingredients, constituents, reaction conditions and so forth used in the specification and claims are to be understood as being modified in all instances by the term “about.” Accordingly, unless indicated to the contrary, the numerical parameters set forth in the specification and attached claims are approximations that may vary depending upon the desired properties sought to be obtained by the subject matter presented herein. At the very least, and not as an attempt to limit the application of the doctrine of equivalents to the scope of the claims, each numerical parameter should at least be construed in light of the number of reported significant digits and by applyin...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
wavelengthsaaaaaaaaaa
wavelengthaaaaaaaaaa
output poweraaaaaaaaaa
Login to View More

Abstract

Near infrared imaging using elastic light scattering and tissue autofluorescence and utilizing interior examination techniques and equipment are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and / or tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

Description

RELATED APPLICATION [0001] This application is a division of U.S. application Ser. No. 10 / 400,024, filed Mar. 25, 2003, entitled “Autofluorescence Detection and Imaging of Bladder Cancer Realized Through a Cystoscope,” which is a Continuation-In-Part of application Ser. No. 10 / 190,231 filed Jul. 5, 2002, and claims priority thereto.[0002] The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.BACKGROUND OF THE INVENTION [0003] 1. Field of the Invention [0004] The present invention relates to a medical diagnostic for the examination of tissue components. Specifically, the present invention relates to an optical imaging method and apparatus for in-vivo and real-time imaging of bladder cancer and determination of tumor margins. [0005] 2. Description of Related Art [0006] Diagnostic medical equipment typical...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61B6/00G01N21/49G01N21/64
CPCA61B1/043A61B1/0638A61B1/307A61B1/313A61B5/0071A61B5/0075A61B1/0669G01N21/49G01N21/6445A61B1/00186A61B1/063A61B1/0646A61B5/0086
Inventor DEMOS, STAVROS G.WHITE, RALPH W. DEVERE
Owner LAWRENCE LIVERMORE NAT SECURITY LLC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com