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Application of composition to adjuvant treatment on infantile eczema

A technology of baby eczema and composition, which is applied in the field of emollients for treating baby eczema, and can solve the problems of avoiding use on the head and face, repeated or aggravated disease, skin atrophy and dryness, etc.

Pending Publication Date: 2016-11-09
贝亲管理(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional drugs for treating infantile eczema usually use topical glucocorticoid preparations to control inflammatory reactions, but such preparations are not suitable for long-term use and should not be used on the head and face, as they can induce fungal skin infections, skin atrophy and dryness, and easily lead to recurrence or aggravation of the disease [6]

Method used

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  • Application of composition to adjuvant treatment on infantile eczema
  • Application of composition to adjuvant treatment on infantile eczema
  • Application of composition to adjuvant treatment on infantile eczema

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1. Preparation of compositions of the present invention

[0024] The concrete composition of composition of the present invention is as follows:

[0025]

[0026] The emollient using the present invention can be manufactured through the following process for use in combination with eczema healing cream to treat infant eczema.

[0027] First, zinc oxide, polymethylsiloxane, and 50% mineral oil are pretreated by a three-roll mill, and the three are fully mixed for later use.

[0028] Next, heat petrolatum and dextrin palmitate / ethylhexanoate to above 100°C to dissolve and mix them into a transparent liquid. Then lower the temperature to 80°C, add paraffin wax and stearyl glycyrrhetinate in turn, and mix well.

[0029] Then, add the pretreated zinc oxide, polymethicone, and mineral oil mixture, and stir evenly. Then add silica dimethyl silylate and the remaining 50% mineral oil, and mix well.

[0030] Finally, after all the above components are mixed even...

Embodiment 2

0.001wt%

[0033] First, zinc oxide, polymethylsiloxane, and 50% mineral oil are pretreated by a three-roll mill, and the three are fully mixed before use.

[0034] Next, heat petrolatum and dextrin palmitate / ethylhexanoate to above 100°C to dissolve and mix them into a transparent liquid. Then lower the temperature to 80°C, add paraffin wax and stearyl glycyrrhetinate in turn, and mix well.

[0035] Then, add the pretreated zinc oxide, polymethylsiloxane, and mineral oil mixture, and stir well. Then add silica dimethyl silylate and the remaining 50% mineral oil, and mix well.

[0036] Finally, after all the above components are mixed evenly, lower the temperature to below 40°C, add squalane, matricaria flower extract, bisabolol and ginger root extract in sequence, and mix well to obtain a white paste

Embodiment 3

0.002wt%

[0039] First, zinc oxide, polymethylsiloxane, and 50% mineral oil are pretreated by a three-roll mill, and the three are fully mixed before use.

[0040] Next, heat petrolatum and dextrin palmitate / ethylhexanoate to above 100°C to dissolve and mix them into a transparent liquid. Then lower the temperature to 80°C, add paraffin wax and stearyl glycyrrhetinate in turn, and mix well.

[0041] Then, add the pretreated zinc oxide, polymethicone, and mineral oil mixture, and stir evenly. Then add silica dimethyl silylate and the remaining 50% mineral oil, and mix well.

[0042] Finally, after all the above components are mixed evenly, lower the temperature to below 40°C, add squalane, matricaria flower extract, bisabolol and ginger root extract in sequence, and mix well to obtain a white paste

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Abstract

The invention relates to application of a composition to preparation of emollient used in cooperation with eczema treating emulsifiable paste for treating infantile eczema. The composition contains bisabolol, ginger extract, matricaria extract, zinc oxide and a liquorice root derivative.

Description

Technical field [0001] The present invention relates to the use of a composition in the auxiliary treatment of infant eczema, and in particular to the use of a composition in the preparation of an emollient used in combination with an eczema healing cream to treat infant eczema. The composition contains bisabolol, ginger extract, chamomile extract, zinc oxide and licorice derivatives. Background technique [0002] Infant eczema is a common skin disease in infants and young children. In traditional Chinese medicine, it is called "tinea tinea", "baby eczema", etc. The incidence rate is relatively high. According to statistics from Beijing Children's Hospital, eczema is the most common skin disease in infants and young children, accounting for about one-third of outpatient visits. It has become the primary disease that plagues children's skin health. [1] . The disease is a chronic, recurrent, itchy disease that makes children emotionally disturbed and affects their sleep. It ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P17/00A61P17/16A61K33/30A61K31/704A61K35/64A61K31/045A61K31/56
CPCA61K36/9068A61K47/24A61K31/045A61K31/56A61K31/704A61K33/30A61K35/63A61K36/185A61K36/232A61K36/28A61K36/284A61K36/538A61K36/634A61K36/708A61K36/716A61K36/75A61K2300/00
Inventor 鲁文嘉庄琳懿顾晴华
Owner 贝亲管理(上海)有限公司
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