The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine decoction for treating a myeloproliferative disorder syndrome. The traditional Chinese medicine decoction is prepared from the following traditional Chinese medicine raw materials by weight percentage: 6-9% of Japanese polygala, 7-10% of cornu bubali, 6-9% of fructus polygoni orientalis, 8-10% of herba rabdosiae, 6-8% of plantain herb, 2-5% of vervain, 5-8% of lalang grass rhizome, 3-5% of prismatomeris tetrandra, 2-4% of lignum dalbergiae odoriferae, 2-5% of herba orostachyos, 3-6% of rhizoma smilacis glabrae, 2-4% of kelp, 2-4% of changium smyrnioides, 2-5% of bunge corydalis herb, 2-4% of fructus gardeniae praeparatus, 1-3% of oviductus ranae, 1-3% of folium artemisiae argyi, 1-3% of agilawood, 2-4% of fructus aurantii immaturus, 4-7% of poria, 2-5% of purslane and 2-4% of pyrrosia lingua. The decoction has a high curative effect on treating the myeloproliferative disorder syndrome, is free of toxic or side effect, and has the effects of clearing away heat and toxic materials, cooling blood, enriching the blood, promoting the circulation of qi, restoring a menstrual flow, stop bleeding by astringency, supporting yang, dissolving phlegm, resolving a hard lump, promoting blood circulation, diminishing swelling, alleviating pain, nourishing yin, tonifying a kidney, filling marrow, strengthening a spleen, nourishing the blood, preventing a cancer and the like, completely suppresses a malignant abnormal clone hyperplasia myeloid tissue, thoroughly restores immunodeficiency of an organism, improves resistance and has a total effective rate of 85.9%.