Plasma membrane and preparing method thereof

Abstract

The invention provides a plasma membrane and a method for preparing a plasma membrane. The plasma membrane is made of plasma collected by patients before or during the operation, and is rapidly and effectively prepared by high-voltage electrospinning technology and has good biocompatibility. Hemostatic agent and tissue adhesive, the membrane containing fibrin glue or platelet-rich plasma has a certain shape, can wrap and cover the wound surface, and is easy to operate. The diaphragm has the functions of promoting wound healing, reducing wound bleeding and reducing scar tissue formation. At the same time, the polymer medical grade material PVA is used, antibiotics and various inducing components are added according to different situations, and various components are released slowly during the degradation process of the material, so as to promote the healing of wounds and fractures, and prevent and control infection. Since both fibrin glue and platelet-rich plasma are extracted from the patient's own blood, they have high biocompatibility, are not prone to immune rejection, have high safety, and reduce the risk of spreading diseases.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a plasma membrane sheet and a preparation method for plasma membrane formation. Background technique [0002] Although the hemostasis technology in modern surgery has been greatly improved, it still cannot meet the clinical needs, and people continue to explore more ideal tissue adhesives. An ideal tissue adhesive must have the following four characteristics: effectiveness, tissue compatibility, safety, and ease of use. [0003] Fibrin glue and platelet-rich plasma are important components of plasma products, and are widely used in surgical operations as ideal tissue sealants and hemostatic agents. Fibrin glue is also called fibrin gel or fibrin sealant, etc. Its main components are fibrinogen, thrombin, and coagulation factors. The components are all natural components in the human body without tissue toxicity. Adhesion, followed by absorption over days to weeks, has a growth...

AI Technical Summary

Problems solved by technology

However, allogeneic or xenogeneic plasma products have the risks of spreading diseases, immune interference, increasing postoperative infection, tumor recurrence and metastasis, etc.

In the processing and preparation technology of plasma products, manufacturers at home and abroad mainly prepare fresh blood into plasma products through complex chemical technology. waste of blood

Surgeons can use colloidal fibrin glue or liquid platelet-rich plasma on the wound surface, but colloidal fibrin glue and liquid platelet-rich plasma are difficult to plastic at the macroscopic level and are easy to lose, and they do not have good microscopic properties. Porosity, less contact area with the wound surface, which affects the material metabolism of the wound surface, thereby affecting its normal function

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