8 results about "Plasma products" patented technology

The present invention relates to systems and methods for optimizing plasma collection volume. A plasma withdrawal system and a method for operating a plasma withdrawal system are provided by which the volume / weight of the anticoagulated plasma collected is optimized. In one example, a nomogram is provided that utilizes the donor hematocrit to calculate the volume / weight of raw plasma within a plasma product having a maximum volume allowed by the FDA nomogram. In a plasma withdrawal process having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the increasing hematocrit of the donor, resulting in a greater total volume of plasma product to be collected during the plasma withdrawal process.

A processing device includes a pump system, a valve system, a centrifuge, and a controller. A fluid flow circuit is mounted to the device to execute a procedure in which whole blood is processed into a red blood cell product, a plasma product, and a platelet concentrate product. The blood is first separated into red blood cells, buffy coat, and plasma using the centrifuge, with the red blood cells and plasma being removed from the centrifuge, while the buffy coat remains in the centrifuge. The fluid remaining in the centrifuge is circulated through the centrifuge to form a homogenous mixture. Once the mixture is formed, it is separated in the centrifuge into platelet concentrate and red blood cells. A platelet product is then collected by using whole blood or previously collected red blood cells to push the platelet concentrate from the centrifuge to a collection container.

A method for preparing therapeutic blood products from pooled plasma donors is provided. The therapeutic blood products include, for example, plasma, plasma proteins, and plasma fractions, in which safety is improved by reducing or eliminating the concentration of donor autoantibodies against FcεRIβ.

The invention relates to a system and a method for optimizing plasma collection volume. A plasma retrieval system and a method for operating a plasma retrieval system are provided by which the volume / weight of collected anticoagulant plasma is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume / weight of raw plasma within a plasma product having a maximum volume allowed by the FDA nomogram. In a plasma extraction process having a plurality of collection phases, after which a re-infusion cycle, in which concentrated red blood cells are returned to the donor, the volume of the plasma product to be collected is calculated before each collection cycle begins to account for an increased hematocrit of the donor, and the volume of the plasma product to be collected is calculated before each collection cycle begins. Thus, the total volume of the plasma product to be collected during the plasma extraction process is larger.

The present application belongs to the technical field of plasma product processing equipment, and particularly relates to a compact dry-wet dual-purpose plasma thawing instrument. The compact dry-wet dual-purpose plasma thawing instrument comprises a shell, a thawing assembly and a shaking driving assembly arranged in the shell. The shell comprises a cover at the top and a bottom plate at the bottom. The thawing assembly comprises a water tank, a thawing water tank and a circulating water pump. The water tank is fixed on the bottom plate. A backwater tank is arranged above the front side of the thawing water tank. The shaking driving assembly comprises a mounting plate, a driving motor, an eccentric wheel, a connecting rod, a linear guide rail sliding block pair and a movable support. The present application optimizes the internal structure design of the product, effectively compresses the number of various supporting and fixing structures, effectively utilizes the internal installation space, shortens the length of the internal circulation system pipeline path, improves the system reaction efficiency, has lower production and preparation cost, smaller volume and mass, and smaller installation and use space, and can flexibly meet the needs of small and medium-sized primary medical or production systems.

The application provides a chylomicron plasma recovery treatment method, in which kaolin is modified by alkali and acid substances in sequence, and then the modified kaolin and diatomite are used to filter chylomicron plasma in sequence, and a filter with a multilayer gradient structure is used when the diatomite is used to treat chylomicron plasma; by the technical scheme, the cholesterol and triglyceride in the chylomicron plasma are significantly reduced, and a plasma product with low turbidity is obtained.

A system and method for collecting plasma comprises a control circuit configured to control operation of the system, the control circuit configured to receive one or more donor parameters. The control circuit estimates a physiological fluid amount of the donor based at least in part on the one or more donor parameters and calculates a target amount of plasma product comprising raw plasma and anticoagulant by multiplying a prestored constant by the estimated physiological fluid amount. The control circuit controls the system to operate draw and return phases to process whole blood into plasma product until a measured amount of plasma product in the collection container meets the target amount of plasma product.

The application discloses a kind of detection method and system for plasma product species and concentration, belong to plasma technical field, comprising: based on the real-time temperature when generating plasma is collected, obtain the spatial temperature distribution diagram in different time plasma reaction cavity inside under different discharge voltages;By simulating the discharge process in plasma reaction cavity, the species and particle number density of main plasma product under short time scale are obtained;Based on temperature distribution diagram and discharge area when generating plasma, according to particle number density, obtain the generation rate of each product inside plasma reaction cavity and the concentration change of substance under long time scale.The application realizes plasma product mode discrimination and product concentration detection under long time scale, the application comprehensively considers the influence of real-time discharge area, temperature field on product concentration calculation, detection process is simple and convenient, provides guarantee for the efficient operation of plasma in industrial application.