Traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal and preparation method of traditional Chinese medicine hydrophilic gel patch

A technology of hydrogel patch and hydrophilic gel, which is applied in the field of medicine and can solve the problems of long conditioning cycle of traditional Chinese medicine, inconvenient medication, and high cost

Inactive Publication Date: 2017-05-10
湖北硅金凝节能减排科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But the above-mentioned method for the treatment of dysmenorrhea has defects: oral administration, inconvenient medication, relatively lar

Method used

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  • Traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal and preparation method of traditional Chinese medicine hydrophilic gel patch
  • Traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal and preparation method of traditional Chinese medicine hydrophilic gel patch
  • Traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal and preparation method of traditional Chinese medicine hydrophilic gel patch

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 of the present invention provides a kind of Chinese medicine hydrophilic gel patch for the treatment of dysmenorrhea, comprising the following components in mass percentage:

[0027] (Extract) Salvia miltiorrhiza extract 1.0%, Polygonum cuspidatum extract 1.0%, Corydalis extract 1.0%, Turmeric extract 1.0%

[0028] (Penetration enhancer) Azone 3.0%, PEG 7.0%

[0029] (Surfactant) Tween 3.0%

[0030] (Binder) Gelatin 1.0%

[0031] (Crosslinking agent) tetrasodium edetate 0.125%, citric acid 0.25%

[0032] (Filler) Kaolin 0.1%

[0033] (Moisturizer) Propylene Glycol 5.0% Glycerin 20%

[0034] (Hydrophilic Gel) Partially Neutralized Sodium Polyacrylate 4.0%

[0035] (Solvent) Water 52.525%.

[0036] The preparation method of the Chinese medicine hydrophilic gel patch for the treatment of dysmenorrhea is as follows:

[0037] Prepare materials according to the following mass percentages: 1.0% of Danshen extract, 1.0% of Polygonum cuspidatum extract, 1.0% ...

Embodiment 2

[0040] Embodiment 2 of the present invention provides a kind of Chinese medicine hydrophilic gel patch for the treatment of dysmenorrhea, comprising the following components in mass percentage:

[0041] (Extract) 3.0% of Danshen Extract, 3.0% of Polygonum cuspidatum Extract, 3.0% of Corydalis Extract, 3.0% of Turmeric Extract

[0042] (Penetration enhancer) Oleic acid 1.0%, Azone 3.0%, PEG 1.0%

[0043] (Surfactant) Tween 2.0%

[0044] (Binder) Gelatin 1.0%

[0045] (Crosslinking agent) aluminum hydroxide 0.075%, tartaric acid 0.25%

[0046] (Filler) Zinc Oxide 0.1%

[0047] (Moisturizer) Propylene Glycol 5.0% Glycerin 25%

[0048] (Hydrophilic Gel) Partially Neutralized Sodium Polyacrylate 4.0%

[0049] (Solvent) Water 45.575%.

[0050] The preparation method of the Chinese medicine hydrophilic gel patch for the treatment of dysmenorrhea is as follows:

[0051] Prepare materials according to the following mass percentages: 3.0% of Salvia miltiorrhiza extract, 3.0% of P...

Embodiment 3

[0054] Embodiment 3 of the present invention provides a kind of Chinese medicine hydrophilic gel patch for the treatment of dysmenorrhea, comprising the following components in mass percentage:

[0055] (Extract) Salvia extract 4.0%, Polygonum cuspidatum extract 4.0%, Corydalis extract 5.0%, Turmeric extract 5.0%

[0056] (Crosslinking agent) aluminum glycinate 0.1%, tetrasodium edetate 0.025%, tartaric acid 0.25%

[0057] (Moisturizer) Propylene Glycol 7.5%, Glycerin 15%

[0058] (Surfactant) Tween 2.0%

[0059] (Penetration enhancer) Azone 3.0%, Urea 3.0%, Mint 0.6%, PEG2.5%

[0060] (Filler) Zinc Oxide 0.1%

[0061] (Binder) CMC-Na 1%

[0062] (Hydrophilic Gel) Partially Neutralized Sodium Polyacrylate 2.5%

[0063] (Solvent) Water 40.425%.

[0064] The preparation method of the Chinese medicine hydrophilic gel patch for the treatment of dysmenorrhea is as follows:

[0065] Prepare materials according to the following mass percentages: 4.0% of Salvia miltiorrhiza extra...

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Abstract

The invention discloses a traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal. The traditional Chinese medicine hydrophilic gel patch comprises the following components in percentage by mass: 1-10% of a salvia miltiorrhiza extract, 1-10% of a polygonum cuspidatum extract, 1-10% of a Corydalis yanhusuo extract, 1-10% of a turmeric extract, 2.5-10% of hydrophilic gel, 0-1% of a cross-linking agent, 20-40% of a moistening agent, 1-12% of a penetration enhancer, 0-5% of a surfactant, 0-0.1% of a filling agent, 1-3% of an adhesive and 40-70% of a solvent. The traditional Chinese medicine hydrophilic gel patch for treating dysmenorrheal of females is capable of regulating menstruation and removing coldness, warming wombs, activating blood and removing stasis, soothing livers and regulating qi and relieving pain, is simple in treatment and convenient to use. The patch is relatively convenient to use, is capable of overcoming the defects that a conventional patch is small in substrate medicine carrying capacity and sensitization can be easily caused, and moreover is relatively good in biocompatibility and peeling property with skin, small in toxic and/or side effect and good in patient compliance.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine hydrophilic gel patch for treating dysmenorrhea and a preparation method thereof. Background technique [0002] Dysmenorrhea is one of the most common gynecological symptoms. It refers to those who experience lower abdominal pain and swelling before and after menstruation or during menstruation, accompanied by backache or other discomforts. The symptoms seriously affect the quality of life. Dysmenorrhea is divided into two types: primary dysmenorrhea and secondary dysmenorrhea. Primary dysmenorrhea refers to dysmenorrhea without organic lesions in reproductive organs, accounting for more than 90% of dysmenorrhea; secondary dysmenorrhea refers to dysmenorrhea caused by pelvic organic diseases. [0003] At present, there are several ways to treat dysmenorrhea: ①Physical therapy: rest adequately, keep warm, use warm pads and hot water bags, etc.; ③ S...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/70A61K47/32A61K47/42A61K47/38A61P15/00A61P29/00
CPCA61K36/9066A61K9/7046A61K36/537A61K36/66A61K36/704A61K47/32A61K2300/00
Inventor 王海波曾慧余志敏王中元
Owner 湖北硅金凝节能减排科技有限公司
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