Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Platelet-enriched plasma, as well as preparation method and application thereof

A technology of platelet-rich plasma and platelet activator, applied in the field of plasma, can solve the problems of high cost, cumbersome preparation steps, limitation of platelet-rich plasma and the like, and achieve the effect of low cost

Active Publication Date: 2017-05-31
李众利
View PDF3 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the high cost and cumbersome preparation steps of platelet-rich plasma derived from whole blood, the application of platelet-rich plasma in mesenchymal stem cells, especially bone marrow mesenchymal stem cells is greatly limited.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Platelet-enriched plasma, as well as preparation method and application thereof
  • Platelet-enriched plasma, as well as preparation method and application thereof
  • Platelet-enriched plasma, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] One aspect of the present invention relates to a method for preparing buffy coat-derived platelet-rich plasma, said method comprising the step of isolating platelet-rich plasma from buffy coat cells.

[0017] The method of the present invention selects buffy coat cells as raw materials to prepare platelet-rich plasma. Buffy coat cells refer to the remaining part of whole blood after separation into concentrated red blood cells and plasma. This part of residual blood is difficult to use due to its complex composition, difficulty in storage and many other reasons, and is generally discarded directly as medical waste. However, the present invention unexpectedly found that using the discarded buffy coat cells instead of whole blood as a raw material can effectively separate and obtain platelet-rich plasma. Traditional platelet-rich plasma is obtained by separating whole blood as a raw material. A large amount of whole blood needs to be consumed in the preparation process, a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides platelet-enriched plasma, as well as a preparation method and application thereof. According to the preparation method of the platelet-enriched plasma, the platelet-enriched plasma is prepared by taking medical waste white membrane layer cells as raw materials. Compared with the traditional preparation method of platelet-enriched plasma derived from whole blood, the preparation method of the platelet-enriched plasma has the advantages that the raw materials can be obtained cheaply and massively, so that preparation cost is greatly reduced and preparation scale is enlarge. In addition, the method provided by the invention integrates the steps of separating platelet-enriched plasma and activating platelet into one step, and the platelet-enriched plasma prepared by the method can be directly used.

Description

technical field [0001] The invention relates to the field of plasma, in particular to a platelet-rich plasma and its preparation method and application. Background technique [0002] Platelet-rich plasma (platelet-rich plasma, PRP) is a plasma component containing a high concentration of platelets obtained by centrifuging whole blood [1] . Kingsley, etc. [2] The concept of platelet-rich plasma was first proposed in 1954, Childs et al. [3] Found that plasma contains platelet-derived growth factors, which can promote cell growth, Okuda et al. [4] It was discovered for the first time that it has the effect of repairing bone defects. At present, it is believed that the platelet content of platelet-rich plasma is more than 3-4 times that of normal human plasma. [5] , and according to the content of leukocytes, it is divided into leukocyte-rich platelet-rich plasma and leukocyte-poor platelet-rich plasma. [0003] Platelet-rich plasma is rich in a variety of growth factors, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12N5/0775
CPCC12N5/0663C12N5/0665C12N5/0667C12N2500/84
Inventor 李众利王克涛朱恒
Owner 李众利
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com