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Testing method of transplanting muscle tendons in reconstruction of cruciate ligaments

A cruciate ligament and testing method technology, applied in the field of medical device biological experiments, can solve the problems of not being able to apply clinically well, not being able to get good healing, not being able to achieve good effects, etc., achieving detailed test data, avoiding delayed healing, and promoting The effect of tendon and bone healing

Inactive Publication Date: 2017-06-30
南京市六合区人民医院
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Problems solved by technology

Due to the lack of blood vessels at the tendon-bone interface, even small injuries will not heal well without the addition of growth factors
It has been reported that in situ reconstruction of the damaged ACL in vivo does not achieve good results.
The use of metal extrusion screws in ACL reconstruction can improve the repair effect to a certain extent, but due to various defects after metal screw implantation at this stage, it is still not well applied in clinical practice

Method used

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  • Testing method of transplanting muscle tendons in reconstruction of cruciate ligaments

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Experimental program
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Embodiment 1

[0036] The test method of transplanted tendon in cruciate ligament reconstruction of the present invention, with miniature pig as experimental animal, specifically comprises the following steps:

[0037] a. ACL biological model construction

[0038] (1) Transect the ACL of the experimental animal, clean the stump, take out the hamstring tendon of the experimental animal, weave and suture the two ends of the hamstring tendon, and trim it into two transplanted tendons;

[0039] (2) Choose two absorbable expansion screws;

[0040] (3) Femoral tunnel: flex the knee joint at 120°, choose the direction of 10 o’clock on the right knee or 2 o’clock on the left knee, use the femoral locator, and place it 6 mm away from the cartilage wall of the posterior femoral condyle; insert the nostril at the center of the original femoral insertion point of the ACL Guide pin, make a femoral bone tunnel with a hollow drill along the direction of the guide pin;

[0041](4) Tibial tunnel: bend the ...

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Abstract

The invention discloses a test method for transplanted tendons in cruciate ligament reconstruction, comprising the following steps: a. ACL biological model construction: (1) taking out the hamstring tendons of experimental animals and trimming them into two transplanted tendons; selecting two expansion screws; (2) Make a femoral tunnel and a tibial tunnel; (3) Put one end of the two grafted tendons into the femoral tunnel and tibial tunnel respectively; (4) Fix the grafted tendon with expansion screws; b. Initial biomechanical measurement: 1) Take experimental animals 2) After preloading and changing the frequency of cyclic loading, pull out the specimen and the two grafted tendons of the biological model respectively, and record the displacement, tensile stiffness, and double stress displacement after cyclic loading , the maximum pull-out load, failure mode, and the degree of tendon cutting; 4) analyze the bone density, failure load, maximum failure load, displacement data, and tensile stiffness of the tendon-bone interface area to obtain the biological mechanical properties.

Description

technical field [0001] The invention relates to the technical field of medical device biological experiment methods, in particular to a test method for transplanted tendon in cruciate ligament reconstruction. Background technique [0002] The anterior cruciate ligament (ACL) of the knee joint is one of the important static and dynamic stability structures of the knee joint, which can prevent tibial anterior displacement, hyperextension and hyperrotation, and prevent related complications after knee joint instability. ACL injury is a common and frequently-occurring disease, which mainly plagues the majority of adolescents and is one of the most common diseases among adolescents. The incidence of ACL injury is very high, especially for people over the age of 16. According to epidemiological surveys, the incidence of ACL rupture is about 0.035%. In recent years, with the popularization of national sports and more and more teenagers participating in sports activities, the incid...

Claims

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Application Information

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IPC IPC(8): G01N3/32
CPCG01N3/32G01N2223/6126
Inventor 刘玉宝林福庆赵清华郭玉祥林禄攀邹瑞蔡小林温传阳施中平张帆胡桂花
Owner 南京市六合区人民医院