Multi-channel evanescent wave all-optical fiber biosensor

Abstract

The invention relates to a multi-channel evanescent wave all-optical fiber biosensor. The biosensor is characterized in that it comprises a flow sample injection system, an optical system and a control circuit and signal processing system; laser emitted by a semiconductor laser unit is collimated and then divided into a plurality of light beams, each light beam is emitted by a corresponding all-optical fiber system to a corresponding sample pool, each optical fiber probe produces fluorescence after excitation, the generated fluorescence signals are collected and filtered by all-optical fiber systems and are then emitted to a photoelectric detector group, the photoelectric detector group converts the collected fluorescence signals of all the optical fiber probes' surfaces into current signals, multi-channel current signals are processed by a micro-signal simulation preamplifier and a multi-channel lock-in amplifier and then sent to a computer, thus realizing simultaneous quantitative analysis of a sample's multiple indexes; and the computer is also connected to a cooperative control module through a parallel processing module, the parallel processing module is also connected to the semiconductor laser unit through a pulse signal generator, and the cooperative control module is in parallel connection with a peristaltic pump and a ten-position valve.

Description

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AI Technical Summary

Benefits of technology

This technology allows us to create miniature devices that use specialized fibers attached to specific chemical substances (biopolymers) or other materials like virus particles). These fibers have unique properties allowing them to interact specifically with these compounds by changing their characteristics during stimulation from lasing pulses to emitting signals containing various modifications called fluors. Fluorescers then emit visible lights when excited by this emission process. A device connected between the samples and testing equipment analyzes each component's response individually while transferring the data continuously without interruption. It also includes a flow filling system where liquid nitrogen gas is injected onto the test specimen before analysis begins. Overall, this technology enables precise identification of many types of material including DNA, proteins, nucleic acids, metabolism products, drugs, solvents, pesticides, gases, liquids, plasma, and others.

Problems solved by technology

This patented technical problem addressed in this patents relates to developing cost-effective and easily usable chemical analyzers capable of accurately identifying different types of harmful materials from complex environments such as soil and waters without being limited resources. Current commercially available devices require large equipment costs and cannot operate efficiently over long periods of time because they rely heavily on chemistry reagents like chloroform liquids and formaldehydes. There is currently no affordable solution for studying multi-analyzer systems that could simultaneously identify several compounds while minimizing their impact on human health.

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