Chinese herbal medicine compound preparation for treating hematemesis caused by liver fire invading the stomach and preparation method thereof

A compound preparation, the technology of anger invading the stomach, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, blood diseases, etc., can solve the problems of lack of pertinence, unsatisfactory effect, long course of treatment, etc., and improve bioavailability. , Helps to absorb, easy to operate

Inactive Publication Date: 2017-09-15

天津市善济宏兴科技发展有限公司

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AI-Extracted Technical Summary

Problems solved by technology

Although there are many types of drugs currently used clinically to treat hematemesis, there are many factors that cause hematemesis, and there are many types of hematemesis, so these drugs are not targe...

Abstract

A Chinese herbal medicine compound preparation for treating hematemesis caused by liver fire invading the stomach and a preparation method thereof are disclosed. The Chinese herbal medicine compound preparation is prepared from the following medicine raw materials by weight: 9-24 parts of Poria cocos, 6-15 parts of Chinese angelica, 9-24 parts of Radix paeoniae Alba, 6-15 parts of moutan bark, 6-15 parts of stir-fried gardenia, 6-15 parts of radix arnebiae seu lithospermi, 6-15 parts of rhizoma bletillae, 6-15 parts of radix curcumae, 9-24 parts of corydalis tuber, 4-10 parts of radix bupleuri, 4-10 parts of mint and 4-10 parts of raw licorice. The Chinese herbal medicine compound preparation is extracted by boiling with water to extract the effective components of the medicine raw materials and keeping the activity of the effective components of the medicine raw materials, the dissolution rate of the effective components of the medicine raw materials is greatly improved, medicine absorption is facilitated, and the bioavailability is also improved. In addition, the Chinese herbal medicine compound preparation is a pure Chinese medicine compound preparation, so that no toxic and side effect is produced after the Chinese herbal medicine compound preparation is taken by a patient for a long time, and the Chinese herbal medicine compound preparation is good in safety. In addition, the preparation method of the Chinese herbal medicine compound preparation is simple in technology and convenient in operation.

Application Domain

Digestive systemBlood disorder +2

Technology Topic

Side effectCompounded preparations +8

Image

Examples

Experimental program(3)

Example Embodiment

[0015] Example 1:

[0016] The traditional Chinese medicine compound preparation for treating hematemesis caused by liver fire in the stomach provided in this embodiment is made of the following raw materials in dosages by weight:

[0017] Poria 9 Angelica 6 White Peony 9 Peony Peel 6 Fried Gardenia 6

[0018] Comfrey 6 White and 6 Turmeric 6 Corydalis 9 Mint 4

[0019] Bupleurum 4 Raw Licorice 4

[0020] The preparation method of the traditional Chinese medicine compound preparation for treating hematemesis caused by liver fire off the stomach is carried out in the following sequence of steps:

[0021] (a) Weigh and mix the drug materials other than peppermint in the above-mentioned drug materials according to the proportion, then add water to soak for 25 minutes, and then start decoction;

[0022] (b) When step (a) the traditional Chinese medicine is decocted for 25 minutes, add mint, continue to decoct for 5-10 minutes, filter and remove the residue, and then prepare the Chinese medicine compound preparation for treating hematemesis caused by liver fire and stomach attack .

[0023] In addition, the traditional Chinese medicine compound preparation can be made into granules, tablets, capsules, syrups, oral liquids, pills and ointments with common pharmaceutical auxiliary materials.

Example Embodiment

[0024] Example 2:

[0025] The traditional Chinese medicine compound preparation for treating hematemesis caused by liver fire in the stomach provided in this embodiment is made of the following raw materials in dosages by weight:

[0026] Poria 24 Angelica 15 White Peony 24 Peony Peel 15 Fried Gardenia 15

[0027] Lithospermum 15 White and 15 Turmeric 15 Corydalis 24 Mint 10

[0028] Bupleurum 10 Raw Licorice 10

[0029] The preparation method is the same as in Example 1.

Example Embodiment

[0030] Example 3:

[0031] The traditional Chinese medicine compound preparation for treating hematemesis caused by liver fire in the stomach provided in this embodiment is made of the following raw materials in dosages by weight:

[0032] Poria 12 Angelica 6-15 White Peony 12 Peony Peel 9 Fried Gardenia 9

[0033] Lithospermum 9 White and 9 Turmeric 9 Corydalis 12 Mint 5

[0034] Bupleurum 5 Raw Licorice 5

[0035] The preparation method is the same as in Example 1.

[0036] The Chinese medicinal compound preparation for treating hematemesis caused by liver fire invading the stomach provided by the present invention is brown to brown; the gas is weak and the taste is slightly bitter. In order to verify the therapeutic effect of the traditional Chinese medicine compound preparation, the present inventors used the above-mentioned Chinese medicine compound preparation to carry out systematic clinical observation on 420 patients suffering from liver fire and gastric hematemesis. Among them, 102 patients were 21-30 years old and 129 were 31-40 years old. For example, there are 189 patients aged 41-50 years old, 150ml each time, 3 times a day, 120 days as a course of treatment. After 1 course of treatment, 198 cases were cured (the bleeding symptoms basically disappeared), accounting for 47.1%; 146 cases were effective (main symptoms improved), accounting for 34.8%; 76 cases were ineffective (main symptoms were not improved), accounting for 18.1%; The effective rate is 81.9%. After 2 courses of treatment, 311 cases were cured, accounting for 74.0%; 79 cases were effective, accounting for 18.8%; 30 cases were ineffective, accounting for 7.1%; the total effective rate was 92.9%.

[0037] At the same time, the inventors analyzed the relationship between treatment effect and age, treatment effect and treatment course, and the analysis results are shown in Table 1 and Table 2, respectively.

[0038] Table 1: The relationship between the therapeutic effect and age of the Chinese medicine compound preparation provided by the present invention

[0039]

[0040] Use the data in Table 1 above as x 2 The test method is used to calculate, and the result is 0.050>P>0.025, which can prove that taking the Chinese medicine compound preparation provided by the present invention to treat liver fire and gastric hematemesis does not change the therapeutic effect of each age group with age.

[0041] Table 2: The relationship between the therapeutic effect of the Chinese medicine compound preparation provided by the present invention and the course of treatment

[0042]

[0043] Use the data in Table 2 above as x 2 Calculated by the test method, the result is P<0.005, which can prove that the use of the Chinese medicine compound preparation provided by the present invention to treat gastric hematemesis caused by liver fire, as the treatment progresses, the cure rate and effective rate are significantly improved.

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Description & Claims & Application Information

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Classification and recommendation of technical efficacy words

High dissolution rate
helps to absorb

Chinese herbal medicine compound preparation for treating hematemesis caused by liver fire invading the stomach and preparation method thereof

AI-Extracted Technical Summary

Problems solved by technology

Abstract

Image

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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