Biodegradable Metal Vascular Stents
A vascular stent and biodegradable technology, applied in the field of metal stents and human vascular stents, can solve problems such as excessive corrosion, loss of stent integrity, and failure to achieve expected results, improve mechanical properties and corrosion resistance, avoid Biosafety risk, effect of slowing down the rate of degradation
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[0018] Firstly, the magnesium alloy of the present application is produced by conventional preparation methods in the field, and the specific composition is shown in Table 1.
[0019] Table 1 Composition list of magnesium alloys
[0020]
[0021] It can be seen that the yield strength and elongation of the magnesium alloy for vascular stents of the present application are both better than those of the WE43 alloy in the prior art. In addition, according to GB / T 16886.5-2003, the in vitro cell (L-929 fibroblast) toxicity test was carried out on the magnesium alloy of samples 1-4, and the results showed that the magnesium alloy degradation products of this application had no effect on cell activity, and the cytotoxicity was 0 grade, showing excellent biocompatibility. However, in Comparative Example 1, because the Sn content was too low, the Sn / Sc≥3 requirement of the present application was not met, and the cytotoxicity was grade 1.
[0022] Sample preparation: ① In vitro t...
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