Rat inflammatory soup stimulation model and establishment method
An inflammation and model technology, applied in the field of medical experiments, can solve problems such as affecting the accuracy of detection experimental data, affecting the success or failure of experiments, and inability to achieve continuous long-term stimulation of the dura mater of rats, and achieve the effect of long stimulation time.
Pending Publication Date: 2017-09-26
于生元 +1
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[0004] However, it is obvious that the traditional rat dura mater electrical stimulation model also has its defects, that is, the electrical stimulation model can only implement effective electrode stimulation to observe the post-stimulation behavior of rats when the electricity is applied; its electrical stimulation is an instantaneous stimulation operation, At the same time, it cannot achieve sustained long-term stimulation of the dura mater of rats
[0005] Under certain experimental requirements, only instantaneous electrode stimulation cannot meet the requirements. At the same time, only the implementation of electrode stimulation will also affect the detection of behavioral long-term data indicators after stimulation and the accuracy of experimental data, and even affect the success or failure of the entire experiment.
[0006] Therefore, in the rat dura mater stimulation model experiment, how to stimulate rats with small damage, short stimulation time, and repeated stimulation experiments has not been found so far.
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[0057] The technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0058] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, ...
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The invention discloses a rat inflammatory soup stimulation model and an establishment method. The model comprises a rat skull, a cannula component and an inflammatory soup injection component. A stimulation hole is formed at the intersection point of the cranial midline and the coronal suture of the rat skull; the cannula component comprises a cap and a inflammatory soup storage tube; the inflammatory soup injection component comprises a cylindrical tube, a connection tube, a conical tube, a slim tube and a micro injector; the micro injector is used for absorbing the inflammatory soup after connection with the inflammatory soup injection component and further used for injecting the inflammatory soup into the inflammatory soup storage tube of the cannula component through the inflammatory soup injection component; the inflammatory soup storage tube of the cannula component is in embedded fit in the stimulation hole; the cap is in threaded connection with the inflammatory soup storage tube. The rat inflammatory soup stimulation model and the establishment method have high-speed running and non-stopping docking functions and have advantages of high docking safety, high equipment safety and the like.
Description
technical field [0001] The invention relates to the technical field of medical experiments, in particular to a rat inflammation soup stimulation model and its establishment method. Background technique [0002] As we all know, rats are one of the ideal and commonly used experimental animals in biology, medical research and teaching. [0003] When rats are subjected to stimulation experiments on the dura mater of the skull, they are generally stimulated by implanting electrodes to establish an electrode model; then the behavior of the rats is observed through the electrical stimulation from the electrodes, and then through behavioral analysis experiments, the desired results are obtained. The experimental form and experimental results. [0004] However, it is obvious that the traditional rat dura mater electrical stimulation model also has its defects, that is, the electrical stimulation model can only implement effective electrode stimulation to observe the post-stimulation...
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IPC IPC(8): A61D7/00
CPCA61D7/00
Inventor 于生元谢敬聃张明洁董钊王晓琳刘若卓陈小燕赵灯法
Owner 于生元