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Product of traditional Chinese medicine gel for treating canine sores and its preparation method

A technology of gel and traditional Chinese medicine, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, and medical preparations containing active ingredients. It can solve the problems of slow absorption speed and release of active ingredients, and overcome poor water absorption. Good bioadhesion, avoiding the effect of stuffy feeling

Active Publication Date: 2021-01-26
SOUTHWEST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In modern pharmacy, gel-based sustained-release and controlled-release dosage forms are suitable for gel drug delivery systems, including hydrophilic drugs, hydrophobic drugs, acidic drugs, macromolecular drugs, etc., which can be obtained from the oral cavity, nasal cavity, Skin and other routes of drug administration, but the traditional Chinese medicine gel has the problem of slow release and absorption of active ingredients, so it is necessary to select appropriate excipients and control the ratio to prepare a traditional Chinese medicine gel for the treatment of sores

Method used

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  • Product of traditional Chinese medicine gel for treating canine sores and its preparation method
  • Product of traditional Chinese medicine gel for treating canine sores and its preparation method
  • Product of traditional Chinese medicine gel for treating canine sores and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1, the preparation method of Ziyu Shengji Gel

[0032] Weigh the medicinal materials respectively according to the following prescription, as follows:

[0033]

[0034]

[0035] Its preparation method comprises the following steps:

[0036] 1) Extraction of medicinal materials: place the prescription amount of comfrey, rhodiola rosea, and angelica dahurica in a 50 (v / v)% ethanol solution equivalent to 8 times the weight of the medicinal materials, soak at 60°C for 12 hours, filter, and collect separately Filtrate Ⅰ and filter residue; then add the prescribed amount of Angelica sinensis, Fangfeng, Shengdi, and licorice to the collected filter residue, then add an aqueous solution equivalent to 10 times the weight of the medicinal materials, extract at 100°C for 3 times, each time for 3 hours, filter, and collect the filtrate Ⅱ, respectively concentrate filtrate Ⅰ and filtrate Ⅱ to clear paste (relative density is 1.32-1.50), set aside;

[0037] 2) Prep...

Embodiment 2

[0039] Embodiment 2, the preparation method of Ziyu Shengji Gel

[0040] Weigh the medicinal materials respectively according to the following prescription, as follows:

[0041]

[0042]

[0043] Its preparation method comprises the following steps:

[0044] 1) Extraction of medicinal materials: place the prescription amount of comfrey, rhodiola rosea, and angelica dahurica in a 50 (v / v)% ethanol solution equivalent to 8 times the weight of the medicinal materials, soak at 60°C for 12 hours, filter, and collect separately Filtrate Ⅰ and filter residue; then add the prescribed amount of Angelica sinensis, Fangfeng, Shengdi, and licorice to the collected filter residue, then add an aqueous solution equivalent to 10 times the weight of the medicinal materials, extract at 100°C for 3 times, each time for 3 hours, filter, and collect the filtrate Ⅱ, respectively concentrate filtrate Ⅰ and filtrate Ⅱ to clear paste (relative density is 1.32-1.50), set aside;

[0045] 2) Prep...

Embodiment 3

[0047] Embodiment 3, the preparation method of Ziyu Shengji Gel

[0048] Weigh the medicinal materials respectively according to the following prescription, as follows:

[0049]

[0050] Its preparation method comprises the following steps:

[0051] 1) Extraction of medicinal materials: place the prescription amount of comfrey, rhodiola rosea, and angelica dahurica in a 50 (v / v)% ethanol solution equivalent to 8 times the weight of the medicinal materials, soak at 60°C for 12 hours, filter, and collect separately Filtrate Ⅰ and filter residue; then add the prescribed amount of Angelica sinensis, Fangfeng, Shengdi, and licorice to the collected filter residue, then add an aqueous solution equivalent to 10 times the weight of the medicinal materials, extract at 100°C for 3 times, each time for 3 hours, filter, and collect the filtrate Ⅱ, respectively concentrate filtrate Ⅰ and filtrate Ⅱ to clear paste (relative density is 1.32-1.50), set aside;

[0052] 2) Preparation of t...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine gel product for treating canine sore and a preparation method thereof, and specifically comprises the steps of firstly extracting comfrey, rhodiola and angelica by warm soaking with ethanol, and then extracting angelica, fenfeng, shengdi and licorice with ethanol. The medicinal residues are mixed and extracted by water extraction, respectively concentrated to clear paste, and then made into a gel with a moisturizing agent, a gel matrix, etc. It can be used for the prevention and treatment of sores, burns, scalds, mosquito bites, etc.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and relates to a preparation method of a traditional Chinese medicine gel for treating canine sores and ulcers, and also relates to a product prepared by the method. Background technique [0002] Chinese veterinary medicine is a drug used to prevent and treat various animal diseases under the guidance of the theory of Chinese veterinary medicine. In China, traditional Chinese medicines such as comfrey and angelica are now used to make "burn oil", which has a significant effect on infected wounds and ulcers such as burns, scalds, and trauma. It is also made into ointment and other dosage forms for clinical use. The ointment is very viscous. If there is a lot of exudate on the affected area, it will easily form a thin film and stick to the wound surface, and it will be easy to bleed when removed. The oil solution can make the wound surface lubricated without hard and uncomfo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K9/06A61K47/10A61K47/38A61K47/32A61P17/02A61K31/045A61K35/618
CPCA61K9/0014A61K9/06A61K31/045A61K35/618A61K36/232A61K36/238A61K36/30A61K36/41A61K36/484A61K36/804A61K47/10A61K47/32A61K47/38A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 刘娟罗艺晨刘丽杨显朝杨庆昌程邓芳
Owner SOUTHWEST UNIV