Composite photothermal conversion material containing silver quantum dots and silver polyacrylate complex

A polyacrylic acid silver and complex technology, which is applied in wave energy or particle radiation treatment materials, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as complex preparation processes, achieve strong absorption, and have good application prospects , the effect of good light-to-heat conversion characteristics

Inactive Publication Date: 2017-11-03
QINGDAO UNIV OF SCI & TECH
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  • Abstract
  • Description
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Problems solved by technology

By preparing silver nanorods with different aspect ratios, the position of the absorption peak can be adjusted to realize the absorption of near-infrared light, but the preparation process is relatively complicated.

Method used

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  • Composite photothermal conversion material containing silver quantum dots and silver polyacrylate complex
  • Composite photothermal conversion material containing silver quantum dots and silver polyacrylate complex

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Experimental program
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Effect test

Embodiment approach

[0016] Under the condition of 25°C, 100 ml of sodium polyacrylate (molecular weight: 3000) aqueous solution with a concentration of 0.15 mol per liter and 100 ml of silver nitrate aqueous solution with a concentration of 0.1 mol per liter were mixed and stirred for 30 minutes to prepare a blue suspension , containing a composite of silver quantum dots and silver polyacrylate, the size of silver quantum dots is 2 to 5 nanometers, with strong absorption in the 600 to 1000 nanometer band, and the maximum absorption wavelength is near 800 nanometers. Suspensions of different concentrations obtained after dilution, as the concentration of the suspension increases, the light absorption intensity increases continuously, such as figure 1 shown. Under the irradiation of a laser with a wavelength of 808 nm and a power of 420 mW, when the mass percent concentration of the suspension is 0.005%, 0.01%, 0.02%, 0.03%, 0.04% and 0.05%, 1 ml of the suspension will be processed within 60 minute...

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Abstract

The invention discloses a composite photothermal conversion material containing silver quantum dots and a silver polyacrylate complex. The silver quantum dots and the silver polyacrylate complex are generated through in-situ chemical reaction and are uniformly compounded together, the formed composite photothermal conversion material shows strong optical adsorption properties and efficient photothermal conversion properties in a near-infrared band and is a photothermal conversion material responding to the near-infrared band. The material includes simple and easy preparation steps, large-scale production is easy to achieve, and the obtained product has the good application prospect in the fields of photothermal treatment and photothermal imaging.

Description

technical field [0001] The invention relates to the field of inorganic functional materials, in particular to a composite photothermal conversion material containing silver quantum dots and polyacrylic acid silver complexes and a preparation method thereof. Background technique [0002] Cancer is one of the main causes of human death at present, and the current treatment methods for cancer are mainly hyperthermia and chemotherapy. Although these two methods can kill cancer cells, they also cause fatal damage to normal tissues and cells, and have high toxic side effects. Photothermal conversion materials can efficiently convert light energy into heat energy. Photothermal conversion materials treated with targeting agents can be selectively adsorbed on cancer cells, and then generate a large amount of heat under laser irradiation to increase the temperature of cancer cells, thereby selectively killing cancer cells and maximizing the Avoid damage to normal cells. The wavelen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K41/00A61K47/58A61P35/00A61K49/00
CPCA61K41/0052A61K49/0002
Inventor 张灿英蒋茜曾文霞吴大雄朱海涛
Owner QINGDAO UNIV OF SCI & TECH
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